Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C5H7NO3.C4H11NO |
| Molecular Weight | 218.2502 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCO.OC(=O)[C@@H]1CCC(=O)N1
InChI
InChIKey=DAEHWWVKPWBXGD-DFWYDOINSA-N
InChI=1S/C5H7NO3.C4H11NO/c7-4-2-1-3(6-4)5(8)9;1-5(2)3-4-6/h3H,1-2H2,(H,6,7)(H,8,9);6H,3-4H2,1-2H3/t3-;/m0./s1
DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
0.1 % single, topical Highest studied dose Dose: 0.1 % Route: topical Route: single Dose: 0.1 % Sources: Page: p.10 |
healthy Health Status: healthy Sources: Page: p.10 |
|
6000 mg 1 times / day multiple, oral Highest studied dose Dose: 6000 mg, 1 times / day Route: oral Route: multiple Dose: 6000 mg, 1 times / day Sources: Page: p.188 |
unhealthy Health Status: unhealthy Condition: Involuntary movement disorders Sources: Page: p.188 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos. | 2001 Aug |
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| The relationship between the interfacial properties of surfactants and their toxicity to aquatic organisms. | 2001 Mar 1 |
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| Improved method for the quality assurance of [C-11]choline. | 2002 Apr |
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| Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. | 2002 Apr |
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| Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. | 2002 Aug |
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| Preparation of phytate-removed deamidated soybean globulins by ion exchangers and characterization of their calcium-binding ability. | 2002 Jan 2 |
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| Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds. | 2002 Mar |
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| [18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine. | 2002 Sep |
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| Reactivity and molecular recognition: amine methylation by an introverted ester. | 2003 Dec 3 |
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| Water-soluble biodegradable cationic polyphosphazenes for gene delivery. | 2003 May 20 |
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| The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity. | 2003 Nov |
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| Highly efficient automated synthesis of [(11)C]choline for multi dose utilization. | 2004 Jun |
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| [11C]Choline as a PET biomarker for assessment of prostate cancer tumor models. | 2004 Jun 1 |
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| Copper (II)-mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries. | 2004 May-Jun |
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| [Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity]. | 2004 Sep-Oct |
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| The role of dimethylaminoethanol in cosmetic dermatology. | 2005 |
|
| The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata). | 2006 Jan |
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| Self-assembly of the unique heterotrimetallic Cu/Co/M complexes possessing triangular antiferromagnetic {Cu2CoPb}2 and linear ferromagnetic {Cu2CoCd2} cores. | 2007 Feb 7 |
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| The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology. | 2007 Mar |
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| Role of the ancillary ligand N,N-dimethylaminoethanol in the sensitization of Eu(III) and Tb(III) luminescence in dimeric beta-diketonates. | 2008 Apr 24 |
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| Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives. | 2008 Jun 26 |
|
| Strong intramolecular Si-N interactions in the chlorosilanes Cl3-nHnSiOCH2CH2NMe2 (n = 1-3). | 2008 Nov 17 |
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| Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008 Nov 22 |
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| Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy. | 2008 Nov-Dec |
|
| Organocadmium aminoalcoholates: synthesis, structure, and materials chemistry. | 2008 Oct 20 |
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| In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation. | 2009 Dec |
|
| Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies. | 2009 Dec |
|
| The pentameric vertex proteins are necessary for the icosahedral carboxysome shell to function as a CO2 leakage barrier. | 2009 Oct 21 |
|
| Efficient automated one-step synthesis of 2-[18F]fluoroethylcholine for clinical imaging: optimized reaction conditions and improved quality controls of different synthetic approaches. | 2010 Apr |
|
| Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard. | 2010 Apr 23 |
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| First efficient synthesis of fluorinated glycidic esters from ketones. | 2010 Feb 19 |
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| Mesotherapy - The french connection. | 2010 Jan |
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| Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming. | 2010 Jul-Aug |
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| The choC gene encoding a putative phospholipid methyltransferase is essential for growth and development in Aspergillus nidulans. | 2010 Jun |
|
| Chloridotris[μ(2)-2-(dimethyl-amino)-ethano-lato]-μ(3)-hydroxido-tri-μ(2)-trifluoro-acetato-tetra-copper(II) tetra-hydro-furan solvate. | 2010 Jun 18 |
|
| In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines. | 2010 Nov |
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| Reduced dimethylaminoethanol in [(18)F]fluoromethylcholine: an important step towards enhanced tumour visualization. | 2010 Nov |
|
| Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release. | 2010 Nov 20 |
|
| Novel pathway to synthesize unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanines. | 2010 Oct 4 |
|
| Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds. | 2010 Sep 15 |
Patents
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DTXSID60946233
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23513-72-6
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ACTIVE MOIETY
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