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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H27NO.ClH
Molecular Weight 345.906
Optical Activity ( - )
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVOMETHADONE HYDROCHLORIDE

SMILES

Cl.CCC(=O)C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=FJQXCDYVZAHXNS-UNTBIKODSA-N
InChI=1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H/t17-;/m1./s1

HIDE SMILES / InChI

Description

levomethadone, or R-(−)-methadone, is the active enantiomer of methadone; having approximately 50x the potency of the S-(+)-enantiomer as well as greater μ-opioid receptor selectivity.

CNS Activity

CNS Active
4,002

Originator

Bockmühl, M.|Ehrhart, G.
13

Approval Year

Unknown
149,124

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Patents

20030175214
3
US20040242617A1
3
US20080221141A1
3
US20090163451A1
3
WO2002000197A1
3

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
PARENT (SALT/SOLVATE)
Structure of LEVOMETHADONE
NIH
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