U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C15H24N2O17P2
Molecular Weight 566.3018
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URIDINE DIPHOSPHATE GLUCOSE

SMILES

OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

InChIKey=HSCJRCZFDFQWRP-JZMIEXBBSA-N
InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
354.0 nM [EC50]
1600.0 nM [EC50]
PubMed

PubMed

TitleDatePubMed
Biological functions of UDP-glucose synthesis in Streptococcus mutans.
1998 May
Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs.
2001 Dec
Active site residues and mechanism of UDP-glucose dehydrogenase.
2004 Jan
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
2006 Oct 4
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
2008
Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.
2009 Jul
Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.
2010 Mar
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.
2015 Jun 5
Patents

Patents

Name Type Language
URIDINE DIPHOSPHATE GLUCOSE
MI   WHO-DD  
Common Name English
UDPG
Common Name English
COGALACTOISOMERASE
WHO-DD  
Common Name English
URIDINE-5'-DIPHOSPHOGLUCOSE
Common Name English
CO-WALDENASE
Common Name English
UDP-GLUCOSE
Common Name English
CO-GALACTOISOMERASE
Common Name English
URIDINE DIPHOSPHATE GLUCOSE [MI]
Common Name English
URIDINE 5'-PYROPHOSPHATE GLUCOSE ESTER
Common Name English
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D-GLUCOPYRANOSYL ESTER
Common Name English
Cogalactoisomerase [WHO-DD]
Common Name English
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D- GLUCOPYRANOSYL ESTER
Common Name English
Uridine diphosphate glucose [WHO-DD]
Common Name English
Code System Code Type Description
WIKIPEDIA
URIDINE DIPHOSPHATE GLUCOSE
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
CHEBI
46229
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
SMS_ID
100000077318
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
EVMPD
SUB13435MIG
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
PUBCHEM
8629
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
CAS
133-89-1
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
MERCK INDEX
m11334
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY Merck Index
DRUG BANK
DB01861
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
EPA CompTox
DTXSID00157902
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-121-4
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
EVMPD
SUB15667MIG
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
FDA UNII
V50K1D7P4Y
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY
CHEBI
18066
Created by admin on Sat Dec 16 01:27:01 GMT 2023 , Edited by admin on Sat Dec 16 01:27:01 GMT 2023
PRIMARY