IOGLUNIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H24I3N3O9
Molecular Weight	807.1113
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C(C)=O)C1=C(I)C(C(=O)NCCO)=C(I)C(NC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=C1I

InChI

InChIKey=ODYPLCHSCOJEIZ-GMYJMXFCSA-N

InChI=1S/C18H24I3N3O9/c1-6(27)24(2)13-10(20)8(17(32)22-3-4-25)9(19)12(11(13)21)23-18(33)16(31)15(30)14(29)7(28)5-26/h7,14-16,25-26,28-31H,3-5H2,1-2H3,(H,22,32)(H,23,33)/t7-,14-,15+,16+/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27908202 | https://www.ncbi.nlm.nih.gov/pubmed/1133913 | https://www.ncbi.nlm.nih.gov/pubmed/50412

Ioglunide is an iodobenzene derivative patented by Laboratoires Andre Guerbet as an oil-based X-ray contrast medium. Iophendylate was commonly used in conventional myelography from the 1940s to the late 1980s before the utilization of computed tomography (CT), magnetic resonance imaging (MRI) and water-soluble contrast agents. Ioglunide, which was never shown to be safe, was initially introduced for use in small amounts for locating spinal tumors. It next appeared on the world scene for high volume, routine use, in diagnosing disc herniations.

Originator

Approval Year

PubMed

Title	Date	PubMed
Intracranial migration of iophendylate four decades after conventional myelography.	2018-06	27908202

Patents

Name

Type

Language

IOGLUNIDE

Official Name

English

3'-((2-HYDROXYETHYL)CARBAMOYL)-2',4',6'-TRIIODO-5'-(N-METHYLACETAMIDO-D-GLUCOANILIDE

Preferred Name

English

ioglunide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28500