Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C25H24FNO6 |
| Molecular Weight | 453.4596 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC(=O)C(=O)NC1=CC(C)=C(OC2=CC(C(O)C3=CC=C(F)C=C3)=C(O)C=C2)C(C)=C1
InChI
InChIKey=FUBBWDWIGBTUPQ-UHFFFAOYSA-N
InChI=1S/C25H24FNO6/c1-4-32-25(31)24(30)27-18-11-14(2)23(15(3)12-18)33-19-9-10-21(28)20(13-19)22(29)16-5-7-17(26)8-6-16/h5-13,22,28-29H,4H2,1-3H3,(H,27,30)
Axitirome (also known as CGS 26214), a thyroid hormone receptor β selective agonist and an LDL receptor function stimulant, has a cholesterol-lowering activity. This drug was in phase I clinical trials for the treatment of hyperlipidemia, but studies were discontinued because of the unexpected side effects.
Originator
Approval Year
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NCI_THESAURUS |
C29703
Created by
admin on Fri Dec 15 15:57:49 GMT 2023 , Edited by admin on Fri Dec 15 15:57:49 GMT 2023
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166559
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300000034073
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CHEMBL159682
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C104715
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7959
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JJ-42
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C75992
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ACTIVE MOIETY
