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Details

Stereochemistry RACEMIC
Molecular Formula C18H18N4O2
Molecular Weight 322.3611
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MESOCARB

SMILES

CC(CC1=CC=CC=C1)[N+]2=NOC([N-]C(=O)NC3=CC=CC=C3)=C2

InChI

InChIKey=OWFUPROYPKGHMH-UHFFFAOYSA-N
InChI=1S/C18H18N4O2/c1-14(12-15-8-4-2-5-9-15)22-13-17(24-21-22)20-18(23)19-16-10-6-3-7-11-16/h2-11,13-14H,12H2,1H3,(H-,19,20,21,23)

HIDE SMILES / InChI
Mesocarb (sydnocarb or 3-(beta-phenylisopropyl)-N-phenylcarbamoylsydnonimine) is a psychomotor stimulant N-alkylated amphetamine derivative. Mesocarb is a selective inhibitor of dopamine uptake, it potently blocks dopamine transporter. It is very likely that mesocarb is being used by drug addicts. Mesocarb is included in the World Anti-Doping Agency’s list of substances and methods that are prohibited in sports. It is used in Russia for the treatment of a variety of neuropsychiatric comorbidities.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q01959
Gene ID: 6531.0
Gene Symbol: SLC6A3
Target Organism: Homo sapiens (Human)
8.3 nM [Ki]
PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

The drug is administered orally, before meals, 1-2 times a day in the first half of the day. Adults: initial dose of 0.005 g / day; if necessary - up to 0,015-0,05 g / day; maintenance dose - 0.005-0.01 g / day, the highest single dose - 0.075 g, daily - 0.15 g
Route of Administration: Oral
Name Type Language
MESOCARB
INN   MART.   WHO-DD  
INN  
Official Name English
SIDNOCARB
Common Name English
MESOCARB [MART.]
Common Name English
mesocarb [INN]
Common Name English
Mesocarb [WHO-DD]
Common Name English
SYDNONE IMINE, 3-(1-METHYL-2-PHENYLETHYL)-N-((PHENYLAMINO)CARBONYL)-
Systematic Name English
1,2,3-OXADIAZOLIUM, 3-(1-METHYL-2-PHENYLETHYL)-5-(((PHENYLAMINO)CARBONYL)AMINO)-, INNER SALT
Systematic Name English
SYDNOCARB
Common Name English
MLR-1017
Code English
SYDNONE IMINE, 3-(.ALPHA.-METHYLPHENETHYL)-N-(PHENYLCARBAMOYL)-
Systematic Name English
DEA NO. 1227
Code English
3-(.ALPHA.-METHYLPHENETHYL)-N-(PHENYLCARBAMOYL)SYDNONE IMINE
Systematic Name English
N-phenyl-N ′-(3-(1-phenylpropan-2-yl)-1,2,3-oxadiazol-3-ium-5-yl)carbamimidate
Systematic Name English
Classification Tree Code System Code
DEA NO. 1227
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
NCI_THESAURUS C66884
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
Code System Code Type Description
SMS_ID
100000081166
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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PUBCHEM
71932
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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ChEMBL
CHEMBL2105246
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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FDA UNII
UMT8MP2NDU
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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EPA CompTox
DTXSID10900961
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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EVMPD
SUB08785MIG
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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INN
3865
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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MESH
C009257
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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NCI_THESAURUS
C83937
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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WIKIPEDIA
MESOCARB
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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CAS
34262-84-5
Created by admin on Sat Dec 16 17:23:10 GMT 2023 , Edited by admin on Sat Dec 16 17:23:10 GMT 2023
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