Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C59H74N18O14 |
Molecular Weight | 1259.3311 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCCC[C@H](NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@H](CO)NC(=O)[C@H](CC4=CNC5=CC=CC=C45)NC(=O)[C@H](CC6=CNC=N6)NC(=O)[C@@H]7CCC(=O)N7)C(=O)N8CCC[C@H]8C(=O)NCC(N)=O
InChI
InChIKey=RTASYRSYWSLWJV-CSYZDTNESA-N
InChI=1S/C59H74N18O14/c60-16-6-5-12-40(59(91)77-17-7-13-47(77)58(90)66-27-48(61)79)70-52(84)41(18-31-23-64-37-10-3-1-8-35(31)37)72-56(88)45(22-50(81)82)75-55(87)44(21-34-26-63-30-68-34)74-57(89)46(28-78)76-53(85)42(19-32-24-65-38-11-4-2-9-36(32)38)71-54(86)43(20-33-25-62-29-67-33)73-51(83)39-14-15-49(80)69-39/h1-4,8-11,23-26,29-30,39-47,64-65,78H,5-7,12-22,27-28,60H2,(H2,61,79)(H,62,67)(H,63,68)(H,66,90)(H,69,80)(H,70,84)(H,71,86)(H,72,88)(H,73,83)(H,74,89)(H,75,87)(H,76,85)(H,81,82)/t39-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1
Peforelin, a decapeptide analog of the natural gonadotropin acts as the natural gonadotropin-releasing hormone (GnRH) agonist. This drug under the brand name Maprelin is used in veterinary to stimulate the reproductive function of sows after weaning piglets in the syndrome of sexual depression.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Influence of synthetic lamprey GnRH-III on gonadotropin release and steroid hormone levels in gilts. | 2010 Dec |
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Effect of a GnRH analogue (Maprelin) on the reproductive performance of gilts and sows. | 2013 Nov |
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Effect of a GnRH analogue (peforelin) on the litter performance of gilts and sows. | 2017 |
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WHO-VATC |
QH01CA95
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8617
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CHEMBL2108043
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UJ8NQ5Z0VX
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Peforelin
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DTXSID30163819
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147859-97-0
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m12183
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16197823
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C170292
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ACTIVE MOIETY