Details
Stereochemistry | RACEMIC |
Molecular Formula | C3H9NO |
Molecular Weight | 75.1097 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(O)CN
InChI
InChIKey=HXKKHQJGJAFBHI-UHFFFAOYSA-N
InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3
Approval Year
Cmax
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
335 mg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2914047/ |
21 mL single, oral dose: 21 mL route of administration: Oral experiment type: SINGLE co-administered: |
ACETONE serum | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
258 mg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2914047/ |
21 mL single, oral dose: 21 mL route of administration: Oral experiment type: SINGLE co-administered: |
ISOPROPYL ALCOHOL serum | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
Overview
CYP3A4 | CYP2C9 | CYP2D6 | hERG |
---|---|---|---|
OverviewOther
Other Inhibitor | Other Substrate | Other Inducer |
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Drug as perpetrator
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
Page: 37.0 |
yes | |||
Page: 59.0 |
yes | |||
Page: 122.0 |
yes | |||
Page: 84.0 |
yes | |||
Page: 150.0 |
yes | |||
Page: 165.0 |
yes | |||
Page: 226.0 |
yes |
PubMed
Title | Date | PubMed |
---|---|---|
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Studies with isopropanolamine, a true substrate. | 1980 Aug 10 |
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Myotropic effects of new proctolin analogues modified in the position 5 of peptide chain in insects. | 2001 Jan-Feb |
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Thermal study of simple amino-alcohol solutions. | 2002 Apr |
|
Vibrational circular dichroism spectrum of 1-amino-2-propanol. | 2002 Jul-Oct |
|
Cytotoxicity of amino alcohols to rat hepatoma-derived Fa32 cells. | 2002 May-Jun |
|
Determination of the enantiomers of ketamine and norketamine in human plasma by enantioselective liquid chromatography-mass spectrometry. | 2003 Aug 25 |
|
Composition and structure of agents responsible for development of water repellency in soils following oil contamination. | 2003 Jul 1 |
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Novel diphenylalkyl piperazine derivatives with high affinities for the dopamine transporter. | 2003 Sep 1 |
|
Determination of the configuration of 3,6-anhydrogalactose and cyclizable alpha-galactose 6-sulfate units in red seaweed galactans. | 2003 Sep 26 |
|
Chiral ligand exchange capillary electrophoresis using borate anion as a central ion. | 2004 Dec |
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Highly enantioselective ruthenium-catalyzed reduction of ketones employing readily available Peptide ligands. | 2004 Jan 5 |
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Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis. | 2004 Mar |
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Persistence and biodegradation of monoethanolamine and 2-propanolamine at an abandoned industrial site. | 2005 May 15 |
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Stability-indicating methods for the determination of piretanide in presence of the alkaline induced degradates. | 2005 Oct 4 |
|
1,4-Benzodiazepine N-nitrosoamidines: useful intermediates in the synthesis of tricyclic benzodiazepines. | 2006 Aug 9 |
|
A novel NADP+-dependent L-1-amino-2-propanol dehydrogenase from Rhodococcus erythropolis MAK154: a promising enzyme for the production of double chiral aminoalcohols. | 2006 Oct |
|
Biomass in the manufacture of industrial products--the use of proteins and amino acids. | 2007 Jun |
|
2-amino-1-propanol versus 1-amino-2-propanol: valence band and C 1s core-level photoelectron spectra. | 2007 Oct 14 |
|
Cloning and expression of the L-1-amino-2-propanol dehydrogenase gene from Rhodococcus erythropolis, and its application to double chiral compound production. | 2008 Sep |
|
Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells. | 2008 Sep-Oct |
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Photolysis of adenosylcobalamin and radical pair recombination in ethanolamine ammonia-lyase probed on the micro- to millisecond time scale by using time-resolved optical absorption spectroscopy. | 2009 Jan 13 |
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Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography. | 2009 Jul 13 |
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Facile fabrication method and characterization of hollow Ag/SiO2 double-shelled spheres. | 2009 Jul 7 |
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Aqueous two-phase extraction of 2,3-butanediol from fermentation broths by isopropanol/ammonium sulfate system. | 2009 Mar |
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N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents. | 2009 May |
|
Comparative application of microwave, ultrasonication, ultracentrifugation and conventional heating for preparation of sample as dinitrophenyl derivative for direct enantioseparation of certain amino alcohols and 1-amino-2-propanol from vitamin B12 hydrolysate on alpha1-acid glycoprotein and beta-cyclodextrin columns. | 2009 Nov 6 |
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Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis. | 2010 Apr 1 |
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Effects of electrochemical reduction reactions on the biodegradation of recalcitrant organic compounds (ROCs) and bacterial community diversity. | 2010 Aug |
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Dental DNA fingerprinting in identification of human remains. | 2010 Jul |
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Enantioselective gel collapsing: a new means of visual chiral sensing. | 2010 Jun 2 |
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Molecular structure and hydrogen bonding of 2-aminoethanol, 1-amino-2-propanol, 3-amino-1-propanol, and binary mixtures with water studied by Fourier transform near-infrared spectroscopy and density functional theory calculations. | 2010 Mar |
|
Charge-transfer complexes of 4-nitrocatechol with some amino alcohols. | 2010 Mar |
|
A phylogenetic estimate for golden moles (Mammalia, Afrotheria, Chrysochloridae). | 2010 Mar 9 |
|
Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis. | 2010 Nov 4 |
Patents
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Classification Tree | Code System | Code | ||
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JECFA EVALUATION |
1-AMINO-2-PROPANOL
Created by
admin on Fri Dec 15 19:31:40 GMT 2023 , Edited by admin on Fri Dec 15 19:31:40 GMT 2023
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 438
Created by
admin on Fri Dec 15 19:31:40 GMT 2023 , Edited by admin on Fri Dec 15 19:31:40 GMT 2023
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 373
Created by
admin on Fri Dec 15 19:31:40 GMT 2023 , Edited by admin on Fri Dec 15 19:31:40 GMT 2023
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CFR |
21 CFR 176.170
Created by
admin on Fri Dec 15 19:31:40 GMT 2023 , Edited by admin on Fri Dec 15 19:31:40 GMT 2023
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19030
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DB02576
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78-96-6
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5224
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C008544
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UE40BY1BZW
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3188
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201-162-7
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DTXSID9021764
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1581
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1-AMINO-2-PROPANOL
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4
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UE40BY1BZW
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1736006
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admin on Fri Dec 15 19:31:40 GMT 2023 , Edited by admin on Fri Dec 15 19:31:40 GMT 2023
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
SUBSTANCE RECORD