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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H13NO5.ClH
Molecular Weight 215.632
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GALACTOSAMINE HYDROCHLORIDE

SMILES

Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO

InChI

InChIKey=CBOJBBMQJBVCMW-NQZVPSPJSA-N
InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1

HIDE SMILES / InChI

Description

Galactosamine is a hexosamine derived from galactose with the molecular formula C6H13NO5. A few amino sugars, including galactosamine, have been shown to kill tumors in the laboratory. It is unlikely to be used in cancer therapy, however. D-galactosamine is a hepatotoxic, or liver-damaging, agent. Researchers studying animal models of liver failure sometimes use D-galactosamine to induce liver damage. Galactosamine is also helpful for researchers studying agents that might protect the liver from damage.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Wistar female rats received 1.4 g/kg of d-galactosamine intraperitoneally
Route of Administration: Intraperitoneal
In Vitro Use Guide
Preincubation of human apoptotic eosinophils with galactosamine (25 mmol/L) significantly inhibited their uptake by both resting and IL-1a–stimulated human small airway epithelial cells (SAEC).