MUROCAINIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H27N3O5
Molecular Weight	377.4348
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(=O)NC1=C(OCCN2CCCCC2)C(OC)=C3OC=CC3=C1OC

InChI

InChIKey=ZXISMUFCWBYFTO-UHFFFAOYSA-N

InChI=1S/C19H27N3O5/c1-20-19(23)21-14-15(24-2)13-7-11-26-16(13)18(25-3)17(14)27-12-10-22-8-5-4-6-9-22/h7,11H,4-6,8-10,12H2,1-3H3,(H2,20,21,23)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7205883 | https://www.ncbi.nlm.nih.gov/pubmed/7175700

Murocainide is aminoalkoxybenzofuran derivative patented by pharmaceutical company Delalande S. A. for ventricular tachycardia treatment. At 5 mg/kg i.v. in dogs Murocainide reversed ouabain-induced ventricular tachycardia.

Originator

Approval Year

PubMed

Title	Date	PubMed
Pharmacokinetics and pharmacodynamics of the antiarrhythmic compound MD750819 in dogs with experimentally induced arrhythmias.	1982-06	7175700
Synthesis and antiarrhythmic activity of new benzofuran derivatives.	1981-02	7205883

Patents

Sample Use Guides

In Vivo Use Guide

Dog: 5 mg/kg

Route of Administration: Intravenous

Name

Type

Language

MUROCAINIDE

Official Name

English

murocainide [INN]

Preferred Name

English

1-(4,7-DIMETHOXY-6-(2-PIPERIDINOETHOXY)-5-BENZOFURANYL)-3-METHYLUREA

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245