Lydimycin

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H14N2O3S
Molecular Weight	242.295
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12CS[C@@]([H])(CC\C=C\C(O)=O)[C@@]1([H])NC(=O)N2

InChI

InChIKey=NZERRTYPTPRCIR-ARSLAPBQSA-N

InChI=1S/C10H14N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h2,4,6-7,9H,1,3,5H2,(H,13,14)(H2,11,12,15)/b4-2+/t6-,7-,9-/m0/s1

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Description
Sources: https://patents.google.com/patent/US3395220

Lydimycin is a biosynthetic product obtained by culturing a lydimycin-producing actinomycete in a suitable aqueous nutrient medium under aerobic conditions. Lydimycin inhibits the growth of Nocardia asteroides, Blastomyces dermatitidis, Geotrichum sp., Phlalophora varrucosa, Cryptococcus neoformans, H Histoplasma capsulatum, and Trichophyton mentagrophytes. Thus, lydimycin is useful alone or in combination with other antifungal or antibiotic agents to prevent the growth of, or reduce the number of, susceptible organisms present in various environments.

Originator

Approval Year

Patents

Name

Type

Language

Lydimycin

Official Name

English

U-15965

Code

English

LYDIMYCIN [USAN]

Common Name

English

LIDIMYCIN

Official Name

English

2-PENTENOIC ACID, 5-(HEXAHYDRO-2-OXO-1H-THIENO(3,4-D)IMIDAZOL-4-YL)-, (3AS(3A.ALPHA.,4.BETA.,6A.ALPHA.))-

Common Name

English

lidimycin [INN]

Common Name

English

U-15,965

Code

English

NSC-127473

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C258