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Details

Stereochemistry ACHIRAL
Molecular Formula C5H4N4O
Molecular Weight 136.1115
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-HYDROXY-7-AZABENZOTRIAZOLE

SMILES

ON1N=NC2=CC=CN=C12

InChI

InChIKey=FPIRBHDGWMWJEP-UHFFFAOYSA-N
InChI=1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Introduction to peptide synthesis.
2002 Aug
Organophosphorus and nitro-substituted sulfonate esters of 1-hydroxy-7-azabenzotriazole as highly efficient fast-acting peptide coupling reagents.
2004 Jan 9
DNA display III. Solid-phase organic synthesis on unprotected DNA.
2004 Jul
Total synthesis of cyclosporin O: exploring the utility of Bsmoc-NMe-amino acid fluorides and KOAt.
2009
Synthesis and application of N-[1-(4-(4-fluorophenyl)-2,6-dioxocyclohexylidene)ethyl] (Fde)-protected amino acids for optimization of solid-phase peptide synthesis using gel-phase (19)F NMR spectroscopy.
2009 Apr
Monoporphyrinate ytterbium(iii) complexes with new ancillary ligands: synthesis, structural analysis and photophysical investigation.
2009 Jun 28
Reactions of monoaryl-substituted methylenecyclobutanes and methylenecyclopropanes with 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and 1-hydroxysuccinimide (HOSu).
2009 Mar 20
Oxyma: an efficient additive for peptide synthesis to replace the benzotriazole-based HOBt and HOAt with a lower risk of explosion.
2009 Sep 21
Sulfonate esters of 1-hydroxypyridin-2(1H)-one and ethyl 2-cyano-2-(hydroxyimino)acetate (oxyma) as effective peptide coupling reagents to replace 1-hydroxybenzotriazole and 1-hydroxy-7-azabenzotriazole.
2010 Apr
Reactivity and applications of new amine reactive cross-linkers for mass spectrometric detection of protein-protein complexes.
2010 Jan 1
Patents
Name Type Language
1-HYDROXY-7-AZABENZOTRIAZOLE
MI  
Systematic Name English
3H-1,2,3-TRIAZOLO(4,5-B)PYRIDINE-3-OL
Systematic Name English
1-HYDROXY-1H-V-TRIAZOLO(4,5-B)PYRIDINE
Common Name English
7-AZA-1-HYDROXYBENZOTRIAZOLE
Common Name English
1-HYDROXY-7-AZABENZOTRIAZOLE [MI]
Common Name English
HOAT
Common Name English
3H-(1,2,3)TRIAZOLO(4,5-B)PYRIDIN-3-OL
Systematic Name English
1-HYDROXYL-7-AZABENZOTRIAZOLE
Systematic Name English
(1,2,3)TRIAZOLO(4,5-B)PYRIDIN-3-OL
Systematic Name English
Code System Code Type Description
PUBCHEM
181649
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
WIKIPEDIA
1-HYDROXY-7-AZABENZOTRIAZOLE
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID0075239
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
CAS
39968-33-7
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
MESH
C435757
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
FDA UNII
TX8XYH09H0
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY
MERCK INDEX
m6118
Created by admin on Sat Dec 16 02:03:19 GMT 2023 , Edited by admin on Sat Dec 16 02:03:19 GMT 2023
PRIMARY Merck Index