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Details

Stereochemistry ACHIRAL
Molecular Formula C10H20N2S4
Molecular Weight 296.5439
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISULFIRAM

SMILES

CCN(CC)C(=S)SSC(=S)N(CC)CC

InChI

InChIKey=AUZONCFQVSMFAP-UHFFFAOYSA-N
InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3

HIDE SMILES / InChI

Description
Curator's Comment:: Description was created based on several sources, including https://www.drugs.com/pro/disulfiram.html

Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in the blood producing highly unpleasant symptoms. Disulfiram blocks the oxidation of alcohol through its irreversible inactivation of aldehyde dehydrogenase, which acts in the second step of ethanol utilization. In addition, disulfiram competitively binds and inhibits the peripheral benzodiazepine receptor, which may indicate some value in the treatment of the symptoms of alcohol withdrawal, however this activity has not been extensively studied. Used for the treatment and management of chronic alcoholism.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Disulfiram

Approved Use

Disulfiram is an aid in the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that supportive and psychotherapeutic treatment may be applied to best advantage.

Launch Date

3.54758394E11
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
1.3 nM
500 mg single, oral
dose: 500 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
DISULFIRAM plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
7.3 h
500 mg single, oral
dose: 500 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
DISULFIRAM plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Disc. AE: Drowsiness, Flushing...
AEs leading to
discontinuation/dose reduction:
Drowsiness
Flushing
Vomiting
Coma
Hypotension
Sinus tachycardia
Arrhythmia
Sources: Page: p.741
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Disc. AE: Somnolence, Nightmares...
AEs leading to
discontinuation/dose reduction:
Somnolence
Nightmares
Auditory hallucinations
Tremor
Dysphagia
Dysarthria
Polyneuropathy
Sources: Page: p.925
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Disc. AE: Confusion, Lethargy...
AEs leading to
discontinuation/dose reduction:
Confusion
Lethargy
Coma
Intellectual disability
Cognitive impairment
Sources: Page: p.390
1000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 1000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1000 mg, 1 times / day
Co-administed with::
temozolomide(150–200 mg/m2 daily on days 1–5 of every 28 day cycle)
Sources: Page: p.4,5
unhealthy, 57
n = 5
Health Status: unhealthy
Condition: Glioblastoma
Age Group: 57
Sex: M+F
Population Size: 5
Sources: Page: p.4,5
DLT: Delirium...
Disc. AE: Ataxia...
Dose limiting toxicities:
Delirium (grade 3, 40%)
AEs leading to
discontinuation/dose reduction:
Ataxia (grade 2-3, 40%)
Sources: Page: p.4,5
500 mg 1 times / day multiple, oral
MTD
Dose: 500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 500 mg, 1 times / day
Co-administed with::
temozolomide(150–200 mg/m2 daily on days 1–5 of every 28 day cycle)
Sources: Page: p.4,5
unhealthy, 57
n = 7
Health Status: unhealthy
Condition: Glioblastoma
Age Group: 57
Sex: M+F
Population Size: 7
Sources: Page: p.4,5
Disc. AE: Delirium...
AEs leading to
discontinuation/dose reduction:
Delirium (grade 3, 14.3%)
Sources: Page: p.4,5
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Other AEs: Drowsiness, Fatigue...
Other AEs:
Drowsiness (below serious, 5 patients)
Fatigue (below serious, 3 patients)
Restlessness (below serious, 4 patients)
Headache (below serious, 5 patients)
Optic neuritis (below serious, 1 patient)
Nausea and vomiting (below serious, 5 patients)
Rash (below serious, 2 patients)
Sources:
AEs

AEs

AESignificanceDosePopulation
Arrhythmia Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Coma Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Drowsiness Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Flushing Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Hypotension Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Sinus tachycardia Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Vomiting Disc. AE
7 g single, oral
Overdose
Dose: 7 g
Route: oral
Route: single
Dose: 7 g
Co-administed with::
Alcohol
Sources: Page: p.741
unhealthy, 24
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 24
Sex: M
Population Size: 1
Sources: Page: p.741
Auditory hallucinations Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Dysarthria Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Dysphagia Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Nightmares Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Polyneuropathy Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Somnolence Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Tremor Disc. AE
37.5 g single, oral
Overdose
Dose: 37.5 g
Route: oral
Route: single
Dose: 37.5 g
Co-administed with::
diazepam, p.o(50 mg, single)
Sources: Page: p.925
unhealthy, 42
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 42
Sex: F
Population Size: 1
Sources: Page: p.925
Cognitive impairment Disc. AE
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Coma Disc. AE
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Confusion Disc. AE
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Intellectual disability Disc. AE
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Lethargy Disc. AE
1500 mg 1 times / day multiple, oral (max)
Overdose
Dose: 1500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1500 mg, 1 times / day
Sources: Page: p.390
unhealthy, 45
n = 1
Health Status: unhealthy
Condition: Alcoholism
Age Group: 45
Sex: M
Population Size: 1
Sources: Page: p.390
Ataxia grade 2-3, 40%
Disc. AE
1000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 1000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1000 mg, 1 times / day
Co-administed with::
temozolomide(150–200 mg/m2 daily on days 1–5 of every 28 day cycle)
Sources: Page: p.4,5
unhealthy, 57
n = 5
Health Status: unhealthy
Condition: Glioblastoma
Age Group: 57
Sex: M+F
Population Size: 5
Sources: Page: p.4,5
Delirium grade 3, 40%
DLT, Disc. AE
1000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 1000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 1000 mg, 1 times / day
Co-administed with::
temozolomide(150–200 mg/m2 daily on days 1–5 of every 28 day cycle)
Sources: Page: p.4,5
unhealthy, 57
n = 5
Health Status: unhealthy
Condition: Glioblastoma
Age Group: 57
Sex: M+F
Population Size: 5
Sources: Page: p.4,5
Delirium grade 3, 14.3%
Disc. AE
500 mg 1 times / day multiple, oral
MTD
Dose: 500 mg, 1 times / day
Route: oral
Route: multiple
Dose: 500 mg, 1 times / day
Co-administed with::
temozolomide(150–200 mg/m2 daily on days 1–5 of every 28 day cycle)
Sources: Page: p.4,5
unhealthy, 57
n = 7
Health Status: unhealthy
Condition: Glioblastoma
Age Group: 57
Sex: M+F
Population Size: 7
Sources: Page: p.4,5
Optic neuritis below serious, 1 patient
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Rash below serious, 2 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Fatigue below serious, 3 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Restlessness below serious, 4 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Drowsiness below serious, 5 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Headache below serious, 5 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Nausea and vomiting below serious, 5 patients
250 mg 1 times / day multiple, oral
Dose: 250 mg, 1 times / day
Route: oral
Route: multiple
Dose: 250 mg, 1 times / day
Sources:
unhealthy, adult
n = 28
Health Status: unhealthy
Condition: Cocaine dependence
Age Group: adult
Population Size: 28
Sources:
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG



OverviewOther

Other InhibitorOther SubstrateOther Inducer


Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
no
no (co-administration study)
Comment: Results show that single-dose disulfiram does not cause clinically significant inhibition of human CYP2C9, 2C19, 2D6, and 3A4 activities in vivo
no
no (co-administration study)
Comment: Results show that single-dose disulfiram does not cause clinically significant inhibition of human CYP2C9, 2C19, 2D6, and 3A4 activities in vivo
no
no (co-administration study)
Comment: Results show that single-dose disulfiram does not cause clinically significant inhibition of human CYP2C9, 2C19, 2D6, and 3A4 activities in vivo
no
no (co-administration study)
Comment: Results show that single-dose disulfiram does not cause clinically significant inhibition of human CYP2C9, 2C19, 2D6, and 3A4 activities in vivo
yes [Ki 12.1 uM]
yes
yes (co-administration study)
Comment: Disulfiram, a selective inhibitor of human hepatic P450 2E1, prevented 80-90% of isoflurane metabolism
PubMed

PubMed

TitleDatePubMed
[Disulfiram neuropathy].
1992 Aug 21
The inhibition of NF-kappaB activation pathways and the induction of apoptosis by dithiocarbamates in T cells are blocked by the glutathione precursor N-acetyl-L-cysteine.
1999 Dec
S-methyl N-butylthiocarbamate sulfoxide: selective carbamoylating agent for mouse mitochondrial aldehyde dehydrogenase.
1999 Nov 1
Disulfiram and buprenorphine for treating cocaine addiction.
2000 Jul
Role of disulfiram in the in vitro inhibition of rat liver mitochondrial aldehyde dehydrogenase.
2000 Oct 1
One-year follow-up of disulfiram and psychotherapy for cocaine-alcohol users: sustained effects of treatment.
2000 Sep
Disulfiram inhibits TNF-alpha-induced cell death.
2000 Sep
Oxidative stress and c-Jun-amino-terminal kinase activation involved in apoptosis of primary astrocytes induced by disulfiram-Cu(2+) complex.
2001 Mar 2
The URICA as a measure of motivation to change among treatment-seeking individuals with concurrent alcohol and cocaine problems.
2002 Dec
[Disulfiram neuropathy. Report of 3 cases].
2002 Sep
[Biological and toxic effects of ethanol: diagnostics and treatment of acute poisonings].
2003
Acute solvent exposure induced activation of cytochrome P4502E1 causes proximal tubular cell necrosis by oxidative stress.
2003 Jun
Effectiveness of some means using against root rot on parsley seedling root.
2004
Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial.
2004 Mar
Accumulation of phenyl boronic acid-carrying telomers on a gold surface.
2004 May 1
Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.
2004 Sep
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.
2005
Acute liver failure: a message found under the skin.
2005 Apr
Pharmacokinetics, safety, and tolerability of a depot formulation of naltrexone in alcoholics: an open-label trial.
2005 Apr 1
Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice.
2005 Nov
[Is Antabus therapy connected with reduced efficacy of nitroglycerin?].
2006 Apr 24
[Disulfiram-induced delirium: a case report].
2006 Dec
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity.
2006 Nov 1
[Optic neuropathy while taking disulfiram].
2006 Oct
Involvement of drug-specific T cells in acute drug-induced interstitial nephritis.
2006 Oct
[New developments in the pharmacotherapy of cocaine dependence].
2006 Sep
Manic episode with psychotic symptoms associated with high dose of disulfiram: a case report.
2007 Apr
Naltrexone and disulfiram in patients with alcohol dependence and current depression.
2007 Apr
Hypotension and ST depression as a result of disulfiram ethanol reaction.
2007 Aug
Disulfiram-induced transient optic and peripheral neuropathy: a case report.
2007 Dec
Adverse effects of excessive nitric oxide on cytochrome c oxidase in lenses of hereditary cataract UPL rats.
2007 Dec 5
Disulfiram is an inhibitor of human purified monoacylglycerol lipase, the enzyme regulating 2-arachidonoylglycerol signaling.
2007 Jul 23
[Acute encephalopathy secondary to treatment with disulfiram].
2007 Oct 1-15
Patents

Sample Use Guides

Usual Adult Dose for Alcohol Dependence -Initial dose: 500 mg orally once a day (this dose is generally continued for the first 1 to 2 weeks) -Maintenance dose: 250 mg orally once a day (range: 125 mg to 500 mg once a day) Maximum dose: 500 mg once a day -Duration of therapy: Depending on the individual, therapy may last months or even years
Route of Administration: Oral
Application of 1mM disulfiram to R. jostii RHA1, gave rise to 4-carboxymuconolactone on the β-ketoadipate pathway
Name Type Language
DISULFIRAM
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD  
INN  
Official Name English
ORA102
Code English
ANTABUSE
Brand Name English
DISULFIRAM [HSDB]
Common Name English
THIOPEROXYDICARBONIC DIAMIDE ((H2N)C(S))(SUB 2) S(SUB 2), TETRAETHYL-
Common Name English
TETRAETHYLTHIOPEROXYDICARBONIC DIAMIDE ((((C(SUB 2)H(SUB 5))(SUB 2)N)C(S))(SUB 2)S(SUB 2))
Common Name English
DISULFIRAM [MART.]
Common Name English
DISULFIRAM [MI]
Common Name English
ORA-102
Code English
NSC-25953
Code English
DISULFIRAM [JAN]
Common Name English
DISULFIRAM [INN]
Common Name English
TETRAETHYLTHIURAM DISULPHIDE
Systematic Name English
DISULFIRAM [USP]
Common Name English
DISULFIRAM [VANDF]
Common Name English
BIS(DIETHYLTHIOCARBAMOYL) DISULPHIDE
Systematic Name English
TETRAETHYLTHIURAM DISULFIDE
Systematic Name English
DISULFIRAM [ORANGE BOOK]
Common Name English
DISULFIRAM [IARC]
Common Name English
BIS(DIETHYLTHIOCARBAMOYL) DISULFIDE
Systematic Name English
DISULFIRAM [EP MONOGRAPH]
Common Name English
DISULFIRAM [EP]
Common Name English
DISULFIRAM [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-VATC QN07BB01
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
WHO-ATC P03AA04
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
FDA ORPHAN DRUG 522516
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
WHO-ATC N07BB01
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
NCI_THESAURUS C2160
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
LIVERTOX 317
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
NDF-RT N0000175679
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
NCI_THESAURUS C1744
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
WHO-ATC P03AA54
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
NDF-RT N0000000183
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
FDA ORPHAN DRUG 771520
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
NCI_THESAURUS C1742
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
Code System Code Type Description
ECHA (EC/EINECS)
202-607-8
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
ChEMBL
CHEMBL964
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
CAS
97-77-8
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
DRUG BANK
DB00822
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
USP_CATALOG
1224008
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY USP-RS
MERCK INDEX
M4677
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY Merck Index
IUPHAR
7168
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
WIKIPEDIA
DISULFIRAM
Created by admin on Fri Jun 25 21:17:20 UTC 2021 , Edited by admin on Fri Jun 25 21:17:20 UTC 2021
PRIMARY
INN
1781
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
DRUG CENTRAL
928
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
RXCUI
3554
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY RxNorm
EVMPD
SUB06326MIG
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
NCI_THESAURUS
C447
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
EPA CompTox
97-77-8
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
MESH
D004221
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
FDA UNII
TR3MLJ1UAI
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
PUBCHEM
3117
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY
HSDB
3317
Created by admin on Fri Jun 25 21:17:19 UTC 2021 , Edited by admin on Fri Jun 25 21:17:19 UTC 2021
PRIMARY