MOCTAMIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H47NO
Molecular Weight	473.7324
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC\C=C/C\C=C/CCCCCCCC(=O)N[C@@H](CC1=CC=C(C)C=C1)C2=CC=CC=C2

InChI

InChIKey=GSPPFJJUCULBDC-FOCYRBLYSA-N

InChI=1S/C33H47NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23-33(35)34-32(31-21-18-17-19-22-31)28-30-26-24-29(2)25-27-30/h7-8,10-11,17-19,21-22,24-27,32H,3-6,9,12-16,20,23,28H2,1-2H3,(H,34,35)/b8-7-,11-10-/t32-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5493099 | https://www.ncbi.nlm.nih.gov/pubmed/1263757

Moctamide is a synthetic linoleamide derivative patented by major Japanese chemical company Sumitomo Chemical Co., Ltd. as hypocholesterolemic agent useful as prophylactics against arteriosclerosis. Administration of Moctamide significantly lowered serum and liver cholesterol and significantly prevented formation of aortic atheromatous changes in animal models.

Originator

Approval Year

PubMed

Title	Date	PubMed
The effect of (--)N-(alpha-phenyl-beta-(p-tolyl)ethyl) linoleamide on experimental atherosclerosis in rabbits.	1970 Sep-Oct	5493099

Patents

Sample Use Guides

In Vivo Use Guide

rabbit: 5–10 mg/day/animal

Route of Administration: Oral

Name

Type

Language

MOCTAMIDE

Official Name

English

NSC-309468

Code

English

MOCTAMIDE [JAN]

Common Name

English

moctamide [INN]

Common Name

English

(-)-N-(P-METHYL-.ALPHA.-PHENYLPHENETHYL)LINOLEAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703