U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula NO3
Molecular Weight 62.0049
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of NITRATE ION

SMILES

[O-][N+]([O-])=O

InChI

InChIKey=NHNBFGGVMKEFGY-UHFFFAOYSA-N
InChI=1S/NO3/c2-1(3)4/q-1

HIDE SMILES / InChI
Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
MAXIMUM STRENGTH SENSITIVE TRUE MINT

Approved Use

builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact; helps protect against cavities.

Launch Date

2009
PubMed

PubMed

TitleDatePubMed
[Nitrate contaminated drinking water from private wells has an impact on the size and functional state of the thyroid gland in schoolchildren].
2000 Nov
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
2000 Oct
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001 Jun
Gallium nitrate accelerates partial thickness wound repair and alters keratinocyte integrin expression to favor a motile phenotype.
2002 Apr
Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin.
2005 Jan 10
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007 Oct
Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.
2008 May
The nitric acid burn trauma of the skin.
2010 Apr
Patents
Name Type Language
NITRATE ION
Common Name English
NITRATE (NO3-)
Common Name English
NITRATE ANION
Common Name English
NITRIC ACID, ION(1-)
Common Name English
NITRATE
Systematic Name English
NITRATE(1-)
Common Name English
ISOSORBIDE MONONITRATE, DILUTED IMPURITY A [EP IMPURITY]
Common Name English
NITRATO
Common Name English
INORGANIC NITRATES
Common Name English
ISOSORBIDE DINITRATE, DILUTED IMPURITY A [EP IMPURITY]
Common Name English
NITRATE ION (NO3-)
Common Name English
Classification Tree Code System Code
DSLD 3333 (Number of products:10)
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
Code System Code Type Description
FDA UNII
T93E9Y2844
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
EVMPD
SUB14657MIG
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
DAILYMED
T93E9Y2844
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
PUBCHEM
943
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
CHEBI
51084
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
EPA CompTox
DTXSID5024217
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
RXCUI
1546271
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY RxNorm
DRUG BANK
DB14049
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
WIKIPEDIA
Nitrate ion
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
CAS
14797-55-8
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY
CHEBI
17632
Created by admin on Fri Dec 15 16:55:59 GMT 2023 , Edited by admin on Fri Dec 15 16:55:59 GMT 2023
PRIMARY