Sefaxersen

Approval Year

Name

Type

Language

Sefaxersen

Official Name

English

DNA,d(P-thio)([2’-O-(2-methoxyethyl)]rA-[2’-O-(2-methoxyethyl)]m5rU-[2’-O-( 2-methoxyethyl)]m5rC-[2’-O-(2-methoxyethyl)]m5rC-[2’-O-(2-methoxyethyl) ]m5rC-A-m5C-G-m5C-m5C-m5C-m5C-T-G-T-[2’-O-(2-methoxyethyl)]m5rC-[2’-O-( 2-methoxyethyl)]m5rC

Systematic Name

English

SEFAXERSEN [USAN]

Common Name

English

IONIS-FB-LRX FREE ACID

Code

English

all-P-ambo-5′-O-{[(6-{5-[(tris{3-[6-(2-acetamido-2-deoxy-β-D-galactopyranosyloxy)hexylamino]-3-oxopropoxymethyl})methyl]amino-5-oxopentanamido}hexyl)]phospho}-2′-O-(2-methoxyethyl)-P-thioadenylyl-(3′-O→5′-O)-2′-O-(2-methoxyethyl)-5-methyl-P-

Systematic Name

English

Code System Code Type Description

CAS

2272975-74-1

Created by admin on Sat Dec 16 14:18:12 UTC 2023 , Edited by admin on Sat Dec 16 14:18:12 UTC 2023

PRIMARY

USAN

KL-233

Created by admin on Sat Dec 16 14:18:13 UTC 2023 , Edited by admin on Sat Dec 16 14:18:13 UTC 2023

PRIMARY

FDA UNII

T87K47QVF3

Created by admin on Sat Dec 16 14:18:12 UTC 2023 , Edited by admin on Sat Dec 16 14:18:12 UTC 2023

PRIMARY

INN

12845

Created by admin on Sat Dec 16 14:18:13 UTC 2023 , Edited by admin on Sat Dec 16 14:18:13 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_6-1_15	10 / 20
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_19	19 / 19

ACTIVE MOIETY


					T87K47QVF3

Sefaxersen