Sefaxersen

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

IONIS-FB-LRX FREE ACID

Preferred Name

English

Sefaxersen

Official Name

English

DNA,d(P-thio)([2?-O-(2-methoxyethyl)]rA-[2?-O-(2-methoxyethyl)]m5rU-[2?-O-( 2-methoxyethyl)]m5rC-[2?-O-(2-methoxyethyl)]m5rC-[2?-O-(2-methoxyethyl) ]m5rC-A-m5C-G-m5C-m5C-m5C-m5C-T-G-T-[2?-O-(2-methoxyethyl)]m5rC-[2?-O-( 2-methoxyethyl)]m5rC-[2?-O-(2-meth

Systematic Name

English

SEFAXERSEN [USAN]

Common Name

English

sefaxersen [INN]

Common Name

English

all-P-ambo-5?-O-{[(6-{5-[(tris{3-[6-(2-acetamido-2-deoxy-?-D-galactopyranosyloxy)hexylamino]-3-oxopropoxymethyl})methyl]amino-5-oxopentanamido}hexyl)]phospho}-2?-O-(2-methoxyethyl)-P-thioadenylyl-(3?-O?5?-O)-2?-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-

Systematic Name

English

Code System Code Type Description

CAS

2272975-74-1

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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SMS_ID

300000041925

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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USAN

KL-233

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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NCI_THESAURUS

C203039

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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FDA UNII

T87K47QVF3

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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INN

12845

Created by admin on Tue Apr 01 22:56:22 GMT 2025 , Edited by admin on Tue Apr 01 22:56:22 GMT 2025

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Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_6-1_15	10 / 20
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_19	19 / 19

ACTIVE MOIETY


					T87K47QVF3