Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H11NO4S |
| Molecular Weight | 253.274 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@]1(CSC(=N1)C2=CC=C(O)C=C2O)C(O)=O
InChI
InChIKey=OEUUFNIKLCFNLN-LLVKDONJSA-N
InChI=1S/C11H11NO4S/c1-11(10(15)16)5-17-9(12-11)7-3-2-6(13)4-8(7)14/h2-4,13-14H,5H2,1H3,(H,15,16)/t11-/m1/s1
Deferitrin is a desferrithiocin-derived hexadentate iron chelator, developed by Genzyme Corp. for the treatment of severe iron overload in people who require repeated erythrocyte transfusion for the management of chronic anemia such as beta-thalassemia major. Development of the drug was halted after phase 1/2 clinical trial due to nephrotoxicity.
Approval Year
| Name | Type | Language | ||
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Preferred Name | English | ||
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Official Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
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FDA ORPHAN DRUG |
178603
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NCI_THESAURUS |
C62357
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| Code System | Code | Type | Description | ||
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T69Y9LDN44
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DTXSID901351209
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8569
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C120073
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QQ-46
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SUB26251
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239101-33-8
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CHEMBL432481
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C76597
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135413558
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EU/3/03/180(WITHDRAWN)
Created by
admin on Mon Mar 31 21:32:24 GMT 2025 , Edited by admin on Mon Mar 31 21:32:24 GMT 2025
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PRIMARY | Please note that this product was withdrawn from the Community Register of designated orphan medicinal products in June 2009 on request of the sponsor. On 12 December 2003, orphan designation (EU/3/03/180) was granted by the European Commission to Genzyme Europe BV, the Netherlands, for 4,5-dihydro-2-(2,4-dihydroxyphenyl)-4-methylthiazole-4(S)-carboxylic acid (GT56-252) for the treatment of chronic iron overload requiring chelation therapy. | ||
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100000091270
Created by
admin on Mon Mar 31 21:32:24 GMT 2025 , Edited by admin on Mon Mar 31 21:32:24 GMT 2025
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PRIMARY |
ACTIVE MOIETY
