METAZAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H12N2O2
Molecular Weight	204.2252
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(C=C1)N2C(=O)NC=C2C

InChI

InChIKey=NHUPEUMBGMETKD-UHFFFAOYSA-N

InChI=1S/C11H12N2O2/c1-8-7-12-11(14)13(8)9-3-5-10(15-2)6-4-9/h3-7H,1-2H3,(H,12,14)

HIDE SMILES / InChI

Description
Sources: https://link.springer.com/book/10.1007/978-1-4757-2085-3#about | https://patents.google.com/patent/US3303199A | https://www.ncbi.nlm.nih.gov/pubmed/3776114

Metazamide is an imidazolone derivative exerting analgesic properties. It affects glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents].	1986 Sep-Oct	3776114

Patents

Name

Type

Language

METAZAMIDE

Official Name

English

metazamide [INN]

Common Name

English

GPA-878

Code

English

1-(P-METHOXYPHENYL)-5-METHYL-4-IMIDAZOLIN-2-ONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257