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Details

Stereochemistry ACHIRAL
Molecular Formula C13H10Cl2O2
Molecular Weight 269.123
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DICHLOROPHEN

SMILES

OC1=C(CC2=C(O)C=CC(Cl)=C2)C=C(Cl)C=C1

InChI

InChIKey=MDNWOSOZYLHTCG-UHFFFAOYSA-N
InChI=1S/C13H10Cl2O2/c14-10-1-3-12(16)8(6-10)5-9-7-11(15)2-4-13(9)17/h1-4,6-7,16-17H,5H2

HIDE SMILES / InChI

Description

Dichlorophene is a halogenated phenolic compound that functions as a bacteriocide and fungicide in cosmetics. Dichlorophene was reported to be used in a total of five cosmetic formulations at concentrations of 0% to 1.0%. Dichlorophen is used in the treatment of tapeworm infestation in man and animals and is the basis of a preparation against athlete’s foot. As a fungicide and bactericide it is recommended for the protection of textiles and materials including horticultural benches and equipment against moulds and algae.

CNS Activity

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
70.0 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Unknown
Curative
Unknown
Curative
Unknown
Curative
Unknown
Curative
Mycota spray

Doses

AEs

PubMed

Sample Use Guides

In Vivo Use Guide
A dose of 5 g is given usually in the morning to treat cestode infections
Route of Administration: Oral
In Vitro Use Guide
0.93 mM dichlorophene killed T. vaginalis within 24 hours in Asami media, Trophozoites of G. lamblia and T. vaginalis were killed in shorter than 10 min with 0.074 mM dichlorophene in serum-free media.