U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H8N2O
Molecular Weight 100.1191
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-NITROSOPYRROLIDINE

SMILES

O=NN1CCCC1

InChI

InChIKey=WNYADZVDBIBLJJ-UHFFFAOYSA-N
InChI=1S/C4H8N2O/c7-5-6-3-1-2-4-6/h1-4H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography-nitrogen chemiluminescence detection.
2010-11
UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test.
2010-09-10
Adsorption of nitrosamines by mesoporous zeolite.
2010-08-15
Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage.
2010-07-27
Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells.
2010-07
The photodissociation dynamics of N-nitrosopyrrolidine from the first and second excited singlet states studied by velocity map imaging.
2010-05-14
Effective nitrosamines trap derived from the in situ carbonized mesoporous silica MCM-41.
2010-04-15
Screening of N-nitrosamines in tap and swimming pool waters using fast gas chromatography.
2010-03
Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat.
2010-01-11
Capturing 1,3-butadiene by the highly ordered Al-containing SBA-15.
2009-11-15
Mass spectrometric analysis of a cyclic 7,8-butanoguanine adduct of N-nitrosopyrrolidine: comparison to other N-nitrosopyrrolidine adducts in rat hepatic DNA.
2009-10
Functional mesoporous material derived from 3D net-linked SBA-15.
2009-07-06
Occurrence and fate of nitrosamines and their precursors in municipal sludge and anaerobic digestion systems.
2009-05-01
Synthesis and crystallization of infinite indium and gallium acetate 1D chain structures and concomitant ethyl acetate hydrolysis.
2009-04-20
Biogenic amines in fish: roles in intoxication, spoilage, and nitrosamine formation--a review.
2009-04
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis.
2009-04
Irradiated Chinese Rugao ham: Changes in volatile N-nitrosamine, biogenic amine and residual nitrite during ripening and post-ripening.
2009-03
Highly sensitive method for determination of N-nitrosamines using high-performance liquid chromatography with online UV irradiation and luminol chemiluminescence detection.
2009-01-02
Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry.
2009-01
Dietary polyphenols protect against N-nitrosamines and benzo(a)pyrene-induced DNA damage (strand breaks and oxidized purines/pyrimidines) in HepG2 human hepatoma cells.
2008-12
Identification of adducts formed in the reactions of 5'-acetoxy-N'-nitrosonornicotine with deoxyadenosine, thymidine, and DNA.
2008-11
Inhibition by vitamin C of apoptosis induced by N-nitrosamines in HepG2 and HL-60 cells.
2008-08
A cell-microelectronic sensing technique for profiling cytotoxicity of chemicals.
2008-05-12
N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS.
2008-01
Protective effect of vitamin C towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
2007-10
Photochemical attenuation of N-nitrosodimethylamine (NDMA) and other nitrosamines in surface water.
2007-09-01
Evaluating the impacts of membrane type, coating, fouling, chemical properties and water chemistry on reverse osmosis rejection of seven nitrosoalklyamines, including NDMA.
2007-09
Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
2007-09
Improving MCM-41 as a nitrosamines trap through a one-pot synthesis.
2007-08-03
Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine.
2007-05-07
Analysis of adducts in hepatic DNA of rats treated with N-nitrosopyrrolidine.
2007-04
Identification of adducts formed in the reaction of alpha-acetoxy-N-nitrosopyrrolidine with deoxyribonucleosides and DNA.
2007-04
Protective role of dietary fibre on N-nitrosopyrrolidine-induced toxicity in hypercholesterolemic rats.
2007-02
Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
2007
Characterization of new nitrosamines in drinking water using liquid chromatography tandem mass spectrometry.
2006-12-15
Fate and transport of N-nitrosamines under conditions simulating full-scale groundwater recharge operations.
2006-12
Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5.
2006-11-10
Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
2006-11-03
Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
2006-07-28
Synthesis and aqueous chemistry of alpha-acetoxy-N-nitrosomorpholine: reactive intermediates and products.
2006-01-06
Occurrence of N-nitrosodimethylamine in South Korean and imported alcoholic beverages.
2005-11
Automated solid-phase extraction and high-performance liquid chromatographic determination of nitrosamines using post-column photolysis and tris(2,2'-bipyridyl) ruthenium(III) chemiluminescence.
2005-06-03
Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine.
2005-01
Adsorption of nitrosamines in acidic solution by zeolites.
2005-01
In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate.
2005-01
Determination of volatile N-nitrosamines in irradiated fermented sausage by gas chromatography coupled to a thermal energy analyzer.
2004-10-29
Detecting N-nitrosamines in drinking water at nanogram per liter levels using ammonia positive chemical ionization.
2004-09-15
Exposure of rat optic nerves to nitric oxide causes protein S-nitrosation and myelin decompaction.
2004-09
N-Nitrosopyrrolidine.
2004
N-Nitrosopyrrolidine.
2002
Name Type Language
N-NITROSOPYRROLIDINE
HSDB   MI  
Systematic Name English
NSC-18797
Preferred Name English
PYR
Common Name English
1-NITROSOPYRROLIDINE
Systematic Name English
PYRROLIDINE, 1-NITROSO-
Systematic Name English
NO-PYR
Common Name English
N-NITROSOPYRROLIDINE [HSDB]
Common Name English
NPYR
Common Name English
N-NITROSOPYRROLIDINE [MI]
Common Name English
N-NITROSOPYRROLIDINE [IARC]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C45402
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
Code System Code Type Description
FDA UNII
SZ4J5WK201
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
PUBCHEM
13591
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
NCI_THESAURUS
C44424
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
HSDB
5116
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
MESH
D009242
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
SMS_ID
300000053510
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
MERCK INDEX
m8000
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY Merck Index
CAS
930-55-2
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
NSC
18797
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
EPA CompTox
DTXSID8021062
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
ECHA (EC/EINECS)
213-218-8
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY