Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.634 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](CC1=CC=C(O)C(Cl)=C1)C(O)=O
InChI
InChIKey=ACWBBAGYTKWBCD-ZETCQYMHSA-N
InChI=1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Increased atherosclerosis in myeloperoxidase-deficient mice. | 2001 Feb |
|
| Artifact-free quantification of free 3-chlorotyrosine, 3-bromotyrosine, and 3-nitrotyrosine in human plasma by electron capture-negative chemical ionization gas chromatography mass spectrometry and liquid chromatography-electrospray ionization tandem mass spectrometry. | 2002 Jan 15 |
|
| Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: the use of N(O,S)-ethoxycarbonyltrifluoroethyl ester derivatives and gas chromatography/mass spectrometry. | 2003 |
|
| Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport. | 2005 Feb 18 |
|
| Trace analysis of oxidized, nitrated, and chlorinated aromatic amino acids by capillary electrophoresis with electroosmotic flow modification allowing large-volume sample stacking. | 2005 May |
|
| Pathways for oxidation of high-density lipoprotein in human cardiovascular disease. | 2006 Jun |
|
| Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system. | 2006 Jun 15 |
|
| Characterization of oxidative pathways in chronic rhinosinusitis and sinonasal polyposis. | 2006 May-Jun |
|
| Depletion of neutrophils reduces neuronal degeneration and inflammatory responses induced by quinolinic acid in vivo. | 2007 Mar |
|
| Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction. | 2007 May 22 |
|
| Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes. | 2008 |
|
| Hypochlorous acid damages histone proteins forming 3-chlorotyrosine and 3,5-dichlorotyrosine. | 2008 May |
|
| Mass spectrometric analysis of HOCl- and free-radical-induced damage to lipids and proteins. | 2008 Oct |
|
| Characterization of pu-erh tea using chemical and metabolic profiling approaches. | 2009 Apr 22 |
|
| Role of endothelial cell stress in the pathogenesis of chronic heart failure. | 2009 Jan 1 |
|
| In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes. | 2009 Nov 17 |
|
| Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis. | 2010 |
|
| Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. | 2010 Apr |
|
| CSF neutrophils are implicated in the development of vasospasm in subarachnoid hemorrhage. | 2010 Apr |
|
| 3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation. | 2010 Dec |
|
| Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein. | 2010 Mar 15 |
|
| A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine. | 2010 May 7 |
|
| Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. | 2010 Nov |
|
| Multivariate modeling identifies neutrophil- and Th17-related factors as differential serum biomarkers of chronic murine colitis. | 2010 Oct 19 |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C73539
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
110992
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
53678
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
7423-93-0
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
SY44C9MINA
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
231-050-3
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
DTXSID801315678
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY | |||
|
C103150
Created by
admin on Sat Dec 16 10:06:33 GMT 2023 , Edited by admin on Sat Dec 16 10:06:33 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD
