Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.634 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](CC1=CC=C(O)C(Cl)=C1)C(O)=O
InChI
InChIKey=ACWBBAGYTKWBCD-ZETCQYMHSA-N
InChI=1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation. | 2010-12 |
|
| Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis. | 2010-11-15 |
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| Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. | 2010-11 |
|
| Multivariate modeling identifies neutrophil- and Th17-related factors as differential serum biomarkers of chronic murine colitis. | 2010-10-19 |
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| Role of nitric oxide and its metabolites as potential markers in lung cancer. | 2010-07 |
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| Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export. | 2010-07 |
|
| A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine. | 2010-05-07 |
|
| Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. | 2010-04 |
|
| CSF neutrophils are implicated in the development of vasospasm in subarachnoid hemorrhage. | 2010-04 |
|
| Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein. | 2010-03-15 |
|
| [Markers of chloric acid (I) in biological systems--identification and properties]. | 2010 |
|
| Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis. | 2010 |
|
| In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes. | 2009-11-17 |
|
| Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure. | 2009-05 |
|
| Characterization of pu-erh tea using chemical and metabolic profiling approaches. | 2009-04-22 |
|
| Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins. | 2009-03 |
|
| Role of endothelial cell stress in the pathogenesis of chronic heart failure. | 2009-01-01 |
|
| Preparation and Characterization of a Polyclonal Antibody against Brominated Protein. | 2009-01 |
|
| Quantification of Modified Tyrosines in Healthy and Diabetic Human Urine using Liquid Chromatography/Tandem Mass Spectrometry. | 2009-01 |
|
| Mass spectrometric analysis of HOCl- and free-radical-induced damage to lipids and proteins. | 2008-10 |
|
| Loss of 3-chlorotyrosine by inflammatory oxidants: implications for the use of 3-chlorotyrosine as a bio-marker in vivo. | 2008-06-20 |
|
| Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome. | 2008-06 |
|
| Hypochlorous acid damages histone proteins forming 3-chlorotyrosine and 3,5-dichlorotyrosine. | 2008-05 |
|
| Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction. | 2008-05 |
|
| 3-chlorotyrosine and 3,5-dichlorotyrosine as biomarkers of respiratory tract exposure to chlorine gas. | 2008-02-14 |
|
| Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes. | 2008 |
|
| Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains. | 2007-12-11 |
|
| Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction. | 2007-05-22 |
|
| The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. | 2007-04 |
|
| Depletion of neutrophils reduces neuronal degeneration and inflammatory responses induced by quinolinic acid in vivo. | 2007-03 |
|
| Chlorinative stress: an under appreciated mediator of neurodegeneration? | 2007-02 |
|
| Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome. | 2006-12 |
|
| Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. | 2006-11-25 |
|
| Characterization of oxidative pathways in chronic rhinosinusitis and sinonasal polyposis. | 2006-07-29 |
|
| Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system. | 2006-06-15 |
|
| Pathways for oxidation of high-density lipoprotein in human cardiovascular disease. | 2006-06 |
|
| Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I. | 2006-04-07 |
|
| Reductive dechlorination of polychlorinated biphenyls as affected by natural halogenated aromatic compounds. | 2006-02 |
|
| Bromination and chlorination reactions of myeloperoxidase at physiological concentrations of bromide and chloride. | 2006-01-15 |
|
| Myeloperoxidase promoter polymorphism -463G is associated with more severe clinical expression of cystic fibrosis pulmonary disease. | 2006 |
|
| The extensible alloscutal cuticle of the tick, Ixodes ricinus. | 2005-10 |
|
| Sputum analysis in diagnosis and management of obstructive airway diseases. | 2005-09 |
|
| Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice. | 2005-07-13 |
|
| Isolation and structure elucidation of the new fungal metabolite (-)-xylariamide A. | 2005-05 |
|
| Trace analysis of oxidized, nitrated, and chlorinated aromatic amino acids by capillary electrophoresis with electroosmotic flow modification allowing large-volume sample stacking. | 2005-05 |
|
| 3-nitrotyrosine attenuates respiratory syncytial virus infection in human bronchial epithelial cell line. | 2005-05 |
|
| Facilitated nitration and oxidation of LDL in cigarette smokers. | 2005-03 |
|
| Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? | 2005-01-28 |
|
| Circulating levels of nitrated apolipoprotein A-I are increased in type 2 diabetic patients. | 2005 |
|
| Urinary eicosanoid and tyrosine derivative concentrations in patients with vasculitides. | 2004-12 |
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NCI_THESAURUS |
C73539
Created by
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| Code System | Code | Type | Description | ||
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110992
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53678
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7423-93-0
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SY44C9MINA
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231-050-3
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DTXSID801315678
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C103150
Created by
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PRIMARY |
SUBSTANCE RECORD
