ISOCOUMARIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H6O2
Molecular Weight	146.1427
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1OC=CC2=C1C=CC=C2

InChI

InChIKey=IQZZFVDIZRWADY-UHFFFAOYSA-N

InChI=1S/C9H6O2/c10-9-8-4-2-1-3-7(8)5-6-11-9/h1-6H

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Radical scavenging and angiotensin converting enzyme inhibitory activities of standardized extracts of Ficus racemosa stem bark.	2010-12	20564493
Immense essence of excellence: marine microbial bioactive compounds.	2010-10-15	21116414
Terpenes from marine-derived fungi.	2010-08-13	20948911
Angiogenesis and chronic kidney disease.	2010-08-05	20687922
Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13.	2010-08	20686255
Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors.	2010-06-15	20472428
3-tert-Butyl-1H-isochromene-1-thione.	2010-05-26	21579538
Biodegradation of ochratoxin a for food and feed decontamination.	2010-05	22069627
Studies on a chlorogenic acid-producing endophytic fungi isolated from Eucommia ulmoides Oliver.	2010-05	20127271
Ochratoxin a: general overview and actual molecular status.	2010-04	22069596
Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90.	2010-03-01	20087915
Chemistry of secondary polyphenols produced during processing of tea and selected foods.	2009-12-28	20161999
Palladium-catalyzed aryl halide carbonylation-intramolecular O-enolate acylation: efficient isocoumarin synthesis, including the synthesis of thunberginol A.	2009-11-28	19885465
Solution-phase synthesis of a diverse isocoumarin library.	2009-10-13	19817453
2-(1,3-Dioxoisoindolin-2-yl)propanoic acid.	2009-10-10	21578285
3-(3-Bromo-benz-yl)-1H-isochromen-1-one.	2009-09-26	21577958
Two new cleistanthane diterpenes and a new isocoumarine from cultures of the basidiomycete Albatrellus confluens.	2009-09	19721259
(2R)-2-(1,3-Dioxoisoindolin-2-yl)-4-(methyl-sulfan-yl)butanoic acid.	2009-07-25	21583673
Isocoumarin glucosides from the scale insect fungus Torrubiella tenuis BCC 12732.	2009-07	19456117
Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.	2009-05	19437244
3-(4-Fluoro-benz-yl)-1H-isochromene-1-thione.	2009-02-11	21582165
Relationship between mast cells and the colitis with relapse induced by trinitrobenzesulphonic acid in Wistar rats.	2009	19436763
2-(2-Fluoro-benzoyl-meth-yl)benzoic acid.	2008-11-08	21581248
Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.	2008-11-04	18983676
2-[(4-Chloro-benz-yl)carbonyl-meth-yl]benzoic acid.	2008-10-25	21581063
3-(3-Chloro-benz-yl)-1H-isochromen-1-one.	2008-09-27	21201213
3-Allyl-2-hydr-oxy-5,6,8-trimethoxy-naphthalene-1,4-dione.	2008-09-13	21201137
Synthesis of 3-substituted isocoumarins and their inhibitory effects on degranulation of RBL-2H3 cells induced by antigen.	2008-09	18758098
Isolation and structure of whiskey polyphenols produced by oxidation of oak wood ellagitannins.	2008-08-27	18672883
3-[(R)-3,3-Dichloro-2-hydroxy-prop-yl]-8-hydr-oxy-6-meth-oxy-1H-isochromen-1-one.	2008-08-20	21201780
Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi.	2008-06	18510362
Syzygium cumini inhibits growth and induces apoptosis in cervical cancer cell lines: a primary study.	2008	22275971
A new isocoumarin from Hypericum annulatum.	2007-10	17852739
Rhodium- and iridium-catalyzed oxidative coupling of benzoic acids with alkynes via regioselective C-H bond cleavage.	2007-07-06	17550295
Isocoumarin Derivatives from the Sea Squirt-derived Fungus Penicillium stoloniferum QY2-10 and the Halotolerant Fungus Penicillium notatum B-52.	2007-07	17703731
An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air.	2007-03-29	17346060
A novel isocoumarin derivative induces mitotic phase arrest and apoptosis of human multiple myeloma cells.	2007-02	16830153
Palladium-catalyzed coupling of allenylphosphonates, phenylallenes, and allenyl esters: remarkable salt effect and routes to novel benzofurans and isocoumarins.	2006-11-24	17109538
Regiocontrolled intramolecular cyclizations of carboxylic acids to carbon-carbon triple bonds promoted by acid or base catalyst.	2006-11-23	17107061
Total synthesis of (+/-)-mitorubrinic acid.	2006-08-03	16869640
Phytochemical studies and antibacterial activity of Centaurium pulchellum Druce.	2006-08	16854716
Mutagenic and cytotoxic effect of planifolin: a naphthopyranone dimer isolated from Paepalanthus planifolius.	2006-08	16271849
Synthesis of 6-O-methyl ether of Scorzocreticin and Scorzocreticoside I, metabolites from Sorzonera cretica.	2006-07-26	16864457
Investigation of a convergent route to purpuromycin: benzofuran formation vs spiroketalization.	2006-07-20	16836376
Tithoniamarin and tithoniamide: a structurally unique isocoumarin dimer and a new ceramide from Tithonia diversifolia.	2006-07-20	16753922
Sensitive and selective PET-based diimidazole luminophore for Zn(II) ions: a structure-activity correlation.	2006-07-10	16813394
Sg17-1-4, a novel isocoumarin from a marine fungus Alternaria tenuis Sg17-1.	2006-06	16915820
2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice.	2006-05	16644677
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator.	2006-02-08	16466576
Heterocycles by PtCl2-catalyzed intramolecular carboalkoxylation or carboamination of alkynes.	2005-11-02	16248631

Patents

Name

Type

Language

ISOCOUMARIN

Preferred Name

English

Code System Code Type Description

CAS

491-31-6