PP1

CC1=CC=C(C=C1)C2=NN(C3=C2C(N)=NC=N3)C(C)(C)C

InChIKey=ZVPDNRVYHLRXLX-UHFFFAOYSA-N

InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)

Targets

Primary Target	Pharmacology	Potency
Tyrosine-protein kinase SRC 19 Target ID: CHEMBL267 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27115835 \| https://www.ncbi.nlm.nih.gov/pubmed/12534346	Inhibitor 8297	17.0 nM [IC50]
Tyrosine-protein kinase LCK 12 Target ID: CHEMBL258 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8557675	Inhibitor 8297	5.0 nM [IC50]
Tyrosine-protein kinase FYN 6 Target ID: CHEMBL1841 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8557675 \| https://www.ncbi.nlm.nih.gov/pubmed/27115835	Inhibitor 8297	6.0 nM [IC50]

Name

Type

Language

PP1

Common Name

English

AGL-1872

Code

English

PYRAZOLOPYRIMIDINE 1

Common Name

English

1-(1,1-DIMETHYLETHYL)-3-(4-METHYLPHENYL)-1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-AMINE

Systematic Name

English

1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-AMINE, 1-(1,1-DIMETHYLETHYL)-3-(4-METHYLPHENYL)-

Systematic Name

English

EI-275

Code

English

PP-1

Common Name

English

PP-1 (ENZYME INHIBITOR)

Common Name

English

Code System Code Type Description

FDA UNII

SA2ND7EHY4