Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H11N3.H3O4P |
| Molecular Weight | 235.1775 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OP(O)(O)=O.CC(C)NC1=NC=CC=N1
InChI
InChIKey=CXEBHWXMQKIKPJ-UHFFFAOYSA-N
InChI=1S/C7H11N3.H3O4P/c1-6(2)10-7-8-4-3-5-9-7;1-5(2,3)4/h3-6H,1-2H3,(H,8,9,10);(H3,1,2,3,4)
Isaxonine (N-isopropyl-amino-2-pyrimidine orthophosphate) is able to accelerate nerve regeneration and functional recovery. Isaxonine has specific affinity for peripheral nerves. It acts directly on the neuron or indirectly by stimulating the production of a growth factor remains unknown. It demonstrates activity in the treatment of neuropathies of various etiology. Isaxonine treatment may be associated with hepatotoxicity.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Presence of covalently bound metabolites on rat hepatocyte plasma membrane proteins after administration of isaxonine, a drug leading to immunoallergic hepatitis in man. | 1989-05 |
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| Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies. | 1985-09-01 |
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| [Protective effect of isaxonine against vincristine-induced neuropathy (author's transl)]. | 1982-04-08 |
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m249
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163093
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S52Q6EHI7F
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DTXSID70215861
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265-845-1
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ACTIVE MOIETY
SUBSTANCE RECORD
