U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Name Type Language
OLEZARSEN
INN   USAN  
Official Name English
ISIS-678354
Code English
olezarsen [INN]
Common Name English
OLEZARSEN [USAN]
Common Name English
IONIS-APOCIII-LRX
Code English
ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)-2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3'
Systematic Name English
AKCEA-APOCIII-LRX
Code English
DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETH
Common Name English
ISIS-APOCIII-LRX
Code English
Code System Code Type Description
USAN
HI-29
Created by admin on Sat Dec 16 18:34:26 GMT 2023 , Edited by admin on Sat Dec 16 18:34:26 GMT 2023
PRIMARY
FDA UNII
S3RS2SA30L
Created by admin on Sat Dec 16 18:34:26 GMT 2023 , Edited by admin on Sat Dec 16 18:34:26 GMT 2023
PRIMARY
NCI_THESAURUS
C180652
Created by admin on Sat Dec 16 18:34:26 GMT 2023 , Edited by admin on Sat Dec 16 18:34:26 GMT 2023
PRIMARY
CAS
2097587-83-0
Created by admin on Sat Dec 16 18:34:26 GMT 2023 , Edited by admin on Sat Dec 16 18:34:26 GMT 2023
PRIMARY
INN
11801
Created by admin on Sat Dec 16 18:34:26 GMT 2023 , Edited by admin on Sat Dec 16 18:34:26 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_6-1_15 10 / 20
2'-O-Methoxyethyl ribose 1_1-1_5;1_16-1_20 10 / 20
Linkage Site Range Site Count
Phosporothioate 1_2-1_20 19 / 19