U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Name Type Language
LUMASIRAN
USAN   INN  
Official Name English
LUMASIRAN [USAN]
Common Name English
RNA, (GM-SP-AM-SP-CM-UM-UM-UM-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)U-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)C-UM-GM-GM-AM-AM-AM-UM-AM-UM-AM), 3'-(((2S,4R)-1-(29-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-14,14-BIS((3-((3-((5-((2-
Systematic Name English
ALN-65585
Code English
((2S,4R)-1-(1-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-16,16-BIS((3-((3-(5-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)PENTANAMIDO)PROPYL)AMINO)-3-OXOPROPOXY)METHYL)-5,11,18-TRIOXO-14-OXA-6,10,17-TRIAZANONACOSAN-29-OYL)-4-HYDROXYPYRRO
Systematic Name English
Lumasiran [WHO-DD]
Common Name English
ALN-G01
Code English
lumasiran [INN]
Common Name English
AD-65585
Code English
ALN-GO1
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 505315
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
Code System Code Type Description
USAN
GH-49
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
CAS
1834610-13-7
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
INN
10684
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
FDA UNII
RZT8C352O1
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
DAILYMED
RZT8C352O1
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
RXCUI
2467140
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
NCI_THESAURUS
C170137
Created by admin on Sat Dec 16 13:40:34 GMT 2023 , Edited by admin on Sat Dec 16 13:40:34 GMT 2023
PRIMARY
Sugar Site Range Site Count
2'-Fluoro-Ribose 1_7;1_9-1_11;1_22;2_2;2_6;2_8-2_9;2_14;2_16 11 / 45
2'-O-Methyl-Ribose 1_1-1_6;1_8;1_12-1_21;2_1;2_3-2_5;2_7;2_10-2_13;2_15;2_17-2_23 34 / 45
Linkage Site Range Site Count
Phosporothioate 1_2-1_3;2_2-2_3;2_22-2_23 6 / 43
Phosphate 1_4-1_22;2_4-2_21 37 / 43