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Details

Stereochemistry ACHIRAL
Molecular Formula K.NO3
Molecular Weight 101.1032
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Potassium nitrate

SMILES

[K+].[O-][N+]([O-])=O

InChI

InChIKey=FGIUAXJPYTZDNR-UHFFFAOYSA-N
InChI=1S/K.NO3/c;2-1(3)4/q+1;-1

HIDE SMILES / InChI

Description

Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Not Provided
511
MAXIMUM STRENGTH SENSITIVE TRUE MINT

Approved Use

builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact; helps protect against cavities.

Launch Date

2009
PubMed

PubMed

TitleDatePubMed
NOS2 is critical to the development of emphysema in Sftpd deficient mice but does not affect surfactant homeostasis.
2014
Fine particulate matter constituents and cardiopulmonary mortality in a heavily polluted Chinese city.
2012-03
Reduced systemic vascular resistance in healthy volunteers with presyncopal symptoms during a nitrate-stimulated tilt-table test.
2011-01
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010-09
Fatal pulmonary edema after acute occupational exposure to nitric acid.
2010-07
The nitric acid burn trauma of the skin.
2010-04
Relationship between endogenous concentrations of vasoactive substances and measures of peripheral vasodilator function in patients with coronary artery disease.
2010-01
Management of unusually extensive esophagogastric corrosive injuries: emergency measures and gastric reconstruction.
2009-05
Acute lung injury after inhalation of nitric acid.
2008-12
An unusual circumstance of internal chemical burn injury - a case report.
2008-10
Water disinfection by-products and pre-labor rupture of membranes.
2008-09-01
Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases.
2008-09
Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.
2008-05
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007-10
Modifications of inflammatory pathways in rat intestine following chronic ingestion of depleted uranium.
2007-08
Oxidative and nitrosative stress in acute ischaemic stroke.
2007-01
Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection.
2007
Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats.
2006-07
Evaluation of possible goitrogenic and anti-thyroidal effect of nitrate, a potential environmental pollutant.
2006-01-31
Immune cell infiltration and broncovascular remodeling after nitric acid nasal instillation in a mouse bronchiolitis obliterans model.
2006-01-07
Clinical diagnostic indicators of renal and bone damage in rats intramuscularly injected with depleted uranium.
2006
Cl- interference with the epithelial Na+ channel ENaC.
2005-09-09
Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids.
2005-08
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005-02-01
[Clinical observation on acupuncture combined with medication for intractable angina pectoris].
2005-02
Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin.
2005-01-10
Rate and extent of percutaneous absorption of sertaconazole nitrate after topical administration.
2005
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004-09
Nitric acid-induced bronchiolitis in rats mimics childhood Bronchiolitis obliterans.
2004-08-12
Acute gastric perforation after acid ingestion.
2002-09
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001-06
[Upper gastrointestinal tract injury caused by ingestion of caustic substances].
2001-04
Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP.
1999-01-05
The assimilatory nitrate reductase from the phototrophic bacterium, Rhodobacter capsulatus E1F1, is a flavoprotein.
1997-09-01
Serum and tissue nitrate levels in murine visceral leishmaniasis correlate with parasite load but not with host protection.
1997-07-01
Incidence of childhood diabetes mellitus in Yorkshire, northern England, is associated with nitrate in drinking water: an ecological analysis.
1997-05
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: involvement of nitric oxide.
1997-05
Therapy of angina pectoris with long-acting nitrates: which agent and when?
1996-05
Dipyridamole enhances interleukin-1beta-stimulated nitric oxide production by cultured rat vascular smooth muscle cells.
1996-02-05
Transient reversal of blood flow in an internal thoracic artery to coronary artery graft during syncope.
1994-08
[Anti-angina therapy of coronary heart disease. Mono- or combination treatment].
1991-05
[Drug treatment of myocardial ischemia].
1991
Nitrates in acute myocardial infarction.
1987
Drug-induced torsade de pointes.
1985-11-01
Addition of nifedipine to maximal nitrate and beta-adrenoreceptor blocker therapy in coronary artery disease.
1985-05-01
Calcium antagonists.
1985
Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine.
1982-02
[Acute and chronic cardiac decompensation: is vasodilator therapy useful?].
1982-01-14
Electrophysiologic properties of hydralazine in man.
1980-09
Proton translocation and the respiratory nitrate reductase of Escherichia coli.
1975-12
Patents

Patents

03931177
6
03957791
6
03973039
6
03978092
6
03987186
7
03988268
6
03992446
6
03994968
6
04005219
6
04010201
7
04021479
14
04036838
7
04038405
6
04049705
7
04053479
6
04055411
6
04066651
6
04066830
6
04067993
6
04071524
14
04093446
6
04096337
6
04107315
6
04118461
7
04120899
6
04126444
6
04136192
6
04141990
6
04154941
14
04159273
8
04166119
6
04174342
6
04174397
6
04177057
6
04178387
12
04180572
7
04180679
6
04196120
7
04199586
6
04200640
6
04279918
13
04415752
6
04555386
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04604267
6
04652559
10
05292387
6
05300511
7
05616586
6
05633248
6
05739129
7
05965679
6
05972136
6
06531502
6
06972286
6
07029504
8
07495021
32
08106064
6
08394837
6
08629277
6
08735322
6
Name Type Language
Potassium nitrate
EP   FCC   HSDB   INCI   JAN   MART.   MI   USP   USP-RS   VANDF   WHO-DD  
INCI  
Official Name English
KALI NITRICUM
HPUS  
Preferred Name English
NITRE
Common Name English
POTASSIUM NITRATE [FCC]
Common Name English
POTASSIUM NITRATE [VANDF]
Common Name English
POTASSIUM NITRATE [MART.]
Common Name English
KALI NITRICUM [HPUS]
Common Name English
INS NO.252
Code English
POTASSIUM NITRATE [HSDB]
Common Name English
NSC-57632
Code English
POTASSIUM NITRATE [JAN]
Common Name English
POTASSIUM NITRATE [EP MONOGRAPH]
Common Name English
Potassium nitrate [WHO-DD]
Common Name English
E-252
Code English
SALTPETRE
Common Name English
POTASSIUM NITRATE [MI]
Common Name English
POTASSIUM NITRATE [USP MONOGRAPH]
Common Name English
POTASSIUM NITRATE [EP IMPURITY]
Common Name English
INS-252
Code English
POTASSIUM NITRATE [USP-RS]
Common Name English
SALTPETER
Common Name English
Classification Tree Code System Code
JECFA EVALUATION INS-252
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-252
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
DSLD 4009 (Number of products:4)
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
NCI_THESAURUS C822
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
CFR 21 CFR 172.160
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
EPA PESTICIDE CODE 76103
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
Code System Code Type Description
ChEMBL
CHEMBL1644029
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
HSDB
1227
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
DRUG CENTRAL
4263
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
CHEBI
64205
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
WIKIPEDIA
POTASSIUM NITRATE
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
EPA CompTox
DTXSID4029692
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
CHEBI
63043
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
MERCK INDEX
m9039
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY Merck Index
ECHA (EC/EINECS)
231-818-8
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
RS_ITEM_NUM
1548350
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
ALTERNATIVE
EVMPD
SUB14988MIG
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
SMS_ID
100000078862
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
DAILYMED
RU45X2JN0Z
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
NSC
57632
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
NCI_THESAURUS
C82074
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
MESH
C023844
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
PUBCHEM
24434
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
RXCUI
34316
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY RxNorm
RS_ITEM_NUM
1548349
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
DRUG BANK
DB11090
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
CAS
7757-79-1
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
FDA UNII
RU45X2JN0Z
Created by admin on Mon Mar 31 18:00:07 GMT 2025 , Edited by admin on Mon Mar 31 18:00:07 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of NITRATE ION
SUBSTANCE RECORD
Structure of Potassium nitrate
NIH
NCATS
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