ELEXACAFTOR

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H34F3N7O4S
Molecular Weight	597.653
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ELEXACAFTOR

Structure Search

SMILES

C[C@@H]1CN(C2=NC(=CC=C2C(=O)NS(=O)(=O)C3=CN(C)N=C3C)N4C=CC(OCC(C)(C)C(F)(F)F)=N4)C(C)(C)C1

InChI

InChIKey=MVRHVFSOIWFBTE-INIZCTEOSA-N

InChI=1S/C26H34F3N7O4S/c1-16-12-25(5,6)35(13-16)22-18(23(37)33-41(38,39)19-14-34(7)31-17(19)2)8-9-20(30-22)36-11-10-21(32-36)40-15-24(3,4)26(27,28)29/h8-11,14,16H,12-13,15H2,1-7H3,(H,33,37)/t16-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

ELEXACAFTOR

Official Name

English

Elexacaftor [WHO-DD]

Common Name

English

ELEXACAFTOR [USAN]

Common Name

English

ELEXACAFTOR [MI]

Common Name

English

VX-445

Code

English

N-(1,3-Dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

Systematic Name

English

elexacaftor [INN]

Common Name

English

3-PYRIDINECARBOXAMIDE, N-((1,3-DIMETHYL-1H-PYRAZOL-4-YL)SULFONYL)-6-(3-(3,3,3-TRIFLUORO-2,2-DIMETHYLPROPOXY)-1H-PYRAZOL-1-YL)-2-((4S)-2,2,4-TRIMETHYL-1-PYRROLIDINYL)-

Code

English

TRIKAFTA COMPONENT ELEXACAFTOR

Brand Name

English

ELEXACAFTOR COMPONENT OF TRIKAFTA

Brand Name

English

ELEXACAFTOR [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/18/2116

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

FDA ORPHAN DRUG

647618

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID901027907

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

PRIMARY

DRUG BANK

DB15444

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

PRIMARY

DAILYMED

RRN67GMB0V

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

PRIMARY

PUBCHEM

134587348

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

PRIMARY

RXCUI

2256951

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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USAN

FG-200

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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INN

11180

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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SMS_ID

100000177684

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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FDA UNII

RRN67GMB0V

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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DRUG CENTRAL

5372

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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CAS

2216712-66-0

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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MERCK INDEX

m12166

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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LACTMED

Elexacaftor, Tezacaftor and Ivacaftor

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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NCI_THESAURUS

C169935

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

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WIKIPEDIA

Elexacaftor

Created by admin on Sat Dec 16 13:22:36 UTC 2023 , Edited by admin on Sat Dec 16 13:22:36 UTC 2023

PRIMARY

ACTIVE MOIETY


					RRN67GMB0V