Silevertinib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C30H30ClFN6O2
Molecular Weight	561.05
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C[C@H]2C[C@]2(C1)C#CC3=CC4=C(C=C3NC(=O)\C=C\CN5CCOCC5)C(NC6=CC=CC(Cl)=C6F)=NC=N4

InChI

InChIKey=LMOVDLRMIRLIJF-TUVXKDNKSA-N

InChI=1S/C30H30ClFN6O2/c1-37-17-21-16-30(21,18-37)8-7-20-14-26-22(29(34-19-33-26)36-24-5-2-4-23(31)28(24)32)15-25(20)35-27(39)6-3-9-38-10-12-40-13-11-38/h2-6,14-15,19,21H,9-13,16-18H2,1H3,(H,35,39)(H,33,34,36)/b6-3+/t21-,30+/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

Silevertinib

Official Name

English

BDTX-1535

Preferred Name

English

(E)-N-(4-((3-chloro-2-fluorophenyl)amino)-7-(((1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-1-yl)ethynyl)quinazolin-6-yl)-4-morpholinobut-2-enamide

Systematic Name

English

silevertinib [INN]

Common Name

English

(2E)-N-[4-[(3-Chloro-2-fluorophenyl)amino]-7-[2-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hex-1-yl]ethynyl]-6-quinazolinyl]-4-(4-morpholinyl)-2-butenamide

Systematic Name

English

EGFR-IN-76

Common Name

English

Code System Code Type Description

INN

13382

Created by admin on Wed Apr 02 12:48:23 GMT 2025 , Edited by admin on Wed Apr 02 12:48:23 GMT 2025

PRIMARY

CAS

2607829-38-7

Created by admin on Wed Apr 02 12:48:23 GMT 2025 , Edited by admin on Wed Apr 02 12:48:23 GMT 2025

PRIMARY

PUBCHEM

156071569

Created by admin on Wed Apr 02 12:48:23 GMT 2025 , Edited by admin on Wed Apr 02 12:48:23 GMT 2025

PRIMARY

FDA UNII

RP9F537KVY

Created by admin on Wed Apr 02 12:48:23 GMT 2025 , Edited by admin on Wed Apr 02 12:48:23 GMT 2025

PRIMARY

ACTIVE MOIETY


					RP9F537KVY

Silevertinib