LEFLUTROZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H10FN5
Molecular Weight	303.2932
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(N1C=NC=N1)(C2=CC=C(C=C2)C#N)C3=CC=C(C=C3)C#N

InChI

InChIKey=PZDLRBUQYWMNBR-UHFFFAOYSA-N

InChI=1S/C17H10FN5/c18-17(23-12-21-11-22-23,15-5-1-13(9-19)2-6-15)16-7-3-14(10-20)4-8-16/h1-8,11-12H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9654648 | https://www.ncbi.nlm.nih.gov/pubmed/9310256 | https://www.ncbi.nlm.nih.gov/pubmed/9365186

CGP-47645 (also known as Leflutrozole) is an orally active non-steroidal aromatase aromatase inhibitor which is under development by Mereo BioPharma and Novartis for the treatment of hypogonadism in men.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Name

Type

Language

LEFLUTROZOLE

Official Name

English

4,4'-(FLUORO-1H-1,2,4-TRIAZOL-1-YLMETHYLENE)BISBENZONITRILE

Systematic Name

English

CGP-47645

Common Name

English

CGP 47,645

Common Name

English

leflutrozole [INN]

Common Name

English

Leflutrozole [WHO-DD]

Common Name

English

Code System Code Type Description

FDA UNII

RCX0IE6EJZ