Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H2O4.Fe |
Molecular Weight | 169.901 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Fe++].[O-]C(=O)\C=C\C([O-])=O
InChI
InChIKey=PMVSDNDAUGGCCE-TYYBGVCCSA-L
InChI=1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/14116934http://www.foodchemadditives.com/products/Ferrous-Lactatehttp://nj.gov/health/eoh/rtkweb/documents/fs/0928.pdfDOI: 10.1021/ja00949a016 Retrived from http://pubs.acs.org/doi/abs/10.1021/ja00949a016https://www.drugs.com/inactive/ferrous-oxide-389.htmlhttp://www.druglead.com/cds/ferrous-iodide.htmlhttp://www.drugfuture.com/chemdata/ferroglycine-sulfate.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/16694502Curator's Comment: description was created based on several sources, including
http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14116934http://www.foodchemadditives.com/products/Ferrous-Lactatehttp://nj.gov/health/eoh/rtkweb/documents/fs/0928.pdfDOI: 10.1021/ja00949a016 Retrived from http://pubs.acs.org/doi/abs/10.1021/ja00949a016https://www.drugs.com/inactive/ferrous-oxide-389.htmlhttp://www.druglead.com/cds/ferrous-iodide.htmlhttp://www.drugfuture.com/chemdata/ferroglycine-sulfate.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/16694502
Curator's Comment: description was created based on several sources, including
http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en
Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.
Originator
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Palliative | Unknown Approved UseUnknown |
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Palliative | Unknown Approved UseUnknown |
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Primary | Ferro Sanol Duodenal Approved UseFerro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia. |
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PubMed
Title | Date | PubMed |
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[Ferrous lactate as an oral iron preparation for therapeutic use]. | 1954 Nov 27 |
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Clinical appraisal of drugs with special reference to a new chelate hematinic. | 1957 Jul 11 |
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[FERROUS ASPARTATE IN THERAPY]. | 1964 Jan 1 |
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Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe. | 1997 Oct |
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Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis. | 2011 Jun 10 |
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Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows. | 2013 Jul |
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A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts. | 2014 |
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Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example. | 2017 Jul 5 |
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Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes. | 2017 Mar 13 |
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Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle. | 2017 May 1 |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.drugs.com/ppa/ferrous-salts.html
Unknown
Route of Administration:
Oral
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Classification Tree | Code System | Code | ||
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WHO-ATC |
B03AD02
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WHO-ATC |
B03AA02
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CFR |
21 CFR 184.1307D
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WHO-VATC |
QB03AA02
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WHO-VATC |
QB03AD02
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CFR |
21 CFR 172.350
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CHEMBL1200640
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205-447-7
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DB14491
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141-01-5
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24941
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R5L488RY0Q
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C61763
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C031621
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C1505
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CONCEPT | Dietary Supplement | ||
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FERROUS FUMARATE
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PRIMARY | Description: A fine, reddish orange or reddish brown powder.Solubility: Slightly soluble in water; very slightly soluble in ethanol (~750 g/l) TS.Category: Iron supplement.Storage: Ferrous fumarate should be kept in a well-closed container.Definition: Ferrous fumarate contains not less than 93.0% and not more than 101.0% of C4H2FeO4, calculated with reference to the dried substance. | ||
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486120
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m5343
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SUB13865MIG
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R5L488RY0Q
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DTXSID7047148
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6433164
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IRON(II) FUMARATE
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100000090445
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4261
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ACTIVE MOIETY
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD