TEROXALENE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H41ClN2O
Molecular Weight	457.091
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TEROXALENE

Structure Search

SMILES

CCC(C)(C)C1=CC=C(OCCCCCCN2CCN(CC2)C3=CC(Cl)=C(C)C=C3)C=C1

InChI

InChIKey=LRQIJOWDNRNLDY-UHFFFAOYSA-N

InChI=1S/C28H41ClN2O/c1-5-28(3,4)24-11-14-26(15-12-24)32-21-9-7-6-8-16-30-17-19-31(20-18-30)25-13-10-23(2)27(29)22-25/h10-15,22H,5-9,16-21H2,1-4H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8070010 | https://www.ncbi.nlm.nih.gov/pubmed/11087578

Teroxalene is a dioxopiperazine derivative with multidrug resistance reversal activity

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Reversal of multidrug resistance by bis(phenylalkyl)amines and structurally related compounds.	1994	8070010

Patents

Patents

Name

Type

Language

TEROXALENE

Official Name

English

1-(3-CHLORO-P-TOLYL)-4-(6-(P-TERT-PENTYLPHENOXY)HEXYL)PIPERAZINE

Common Name

English

teroxalene [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

Code System Code Type Description

EPA CompTox

DTXSID40163643

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PUBCHEM

19705

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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FDA UNII

R4ZID09918

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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INN

2170

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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SMS_ID

100000082713

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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NCI_THESAURUS

C152571

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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ChEMBL

CHEMBL2111143

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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CAS

14728-33-7

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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EVMPD

SUB10931MIG

Created by admin on Fri Dec 15 18:18:11 GMT 2023 , Edited by admin on Fri Dec 15 18:18:11 GMT 2023

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ACTIVE MOIETY


					R4ZID09918

SALT/SOLVATE (PARENT)


					LYL9ES50QE

TEROXALENE HYDROCHLORIDE