ISOAMINILE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C16H24N2
Molecular Weight	244.3752
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ISOAMINILE

Structure Search

SMILES

CC(C)C(CC(C)N(C)C)(C#N)C1=CC=CC=C1

InChI

InChIKey=WFLSCFISQHLEED-UHFFFAOYSA-N

InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3

HIDE SMILES / InChI

Description
Sources: http://home.intekom.com/pharm/hmr/peraconx.html

Isoaminile is a cough suppressant that acts by influencing the cough centre.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://home.intekom.com/pharm/hmr/peraconx.html	Primary		Approved 8429	PERACON Approved Use For the alleviation of cough.

PubMed

PubMed

Title	Date	PubMed
[Clinical comparison of a new antitussive substance (peracon) with codeine & dicodide].	1959 May	13676089
Isoaminile citrate as a cough suppressant.	1966 Mar	5905421
Some cases of acute intoxications from compulsive use of isoaminile.	1979 Sep	518294

Sample Use Guides

In Vivo Use Guide

One to two medicine measurefuls (5 to 10 mL) three to four times daily.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

ISOAMINILE

Official Name

English

ISOAMINILE [MI]

Common Name

English

4-DIMETHYLAMINO-2-ISOPROPYL-2-PHENYLVALERONITRILE

Systematic Name

English

ISOAMINILE [MART.]

Common Name

English

.ALPHA.-(2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-(1-METHYLETHYL)BENZENEACETONITRILE

Systematic Name

English

2C-B-AN

Common Name

English

Isoaminile [WHO-DD]

Common Name

English

3-CYANO-5-DIMETHYLAMINO-3-PHENYL-2-METHYLHEXANE

Systematic Name

English

isoaminile [INN]

Common Name

English

.ALPHA.-(.BETA.-DIMETHYLAMINOPROPYL)-.ALPHA.-ISOPROPYLPHENYLACETONITRILE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QR05DB04

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

WHO-ATC

R05DB04

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

NCI_THESAURUS

C66917

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

Code System Code Type Description

INN

1076

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EPA CompTox

DTXSID5057830

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MESH

C011001

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EVMPD

SUB08310MIG

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ECHA (EC/EINECS)

201-033-5

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DRUG BANK

DB08944

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SMS_ID

100000083362

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MERCK INDEX

m6425

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Merck Index

PUBCHEM

6481

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FDA UNII

R4823W2PQL

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ChEMBL

CHEMBL2105002

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MANUFACTURER PRODUCT INFORMATION

2C-B-AN

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

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It is thought to be a pro-drug for 2C-B described in Daniel Trachsels book "Phenethylamine : Von der Struktur zur Funktion"; the normal dose should be somewhere between 50-100mg.

WIKIPEDIA

ISOAMINILE

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

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CAS

77-51-0

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RXCUI

27866

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RxNorm

NCI_THESAURUS

C83839

Created by admin on Fri Dec 15 16:02:56 GMT 2023 , Edited by admin on Fri Dec 15 16:02:56 GMT 2023

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DRUG CENTRAL

1487

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ACTIVE MOIETY


					R4823W2PQL