U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Cl.Sn
Molecular Weight 189.616
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STANNOUS CHLORIDE ANHYDROUS

SMILES

[Cl-].[Cl-].[SnH2++]

InChI

InChIKey=YHOLMJGIIYTMRY-UHFFFAOYSA-L
InChI=1S/2ClH.Sn.2H/h2*1H;;;/q;;+2;;/p-2

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including: https://www.ncbi.nlm.nih.gov/pubmed/17645550 http://www.pharmacytimes.com/publications/issue/2014/august2014/r648_august2014 https://en.wikipedia.org/wiki/Tin(II)_fluoride

Readily soluble in water, SnF2 is hydrolysed. At low concentration, it forms species such as SnOH+, Sn(OH)2 and Sn(OH)3−. At higher concentrations, predominantly polynuclear species are formed, including Sn2(OH)22+ and Sn3(OH)42+. Aqueous solutions readily oxidise to form insoluble precipitates of SnIV, which are ineffective as a dental prophylactic. Tin(II) fluoride, commonly referred to commercially (with tin(II) in Latin) as stannous fluoride, is a chemical compound with the formula SnF2. It is a colorless solid used as an ingredient in toothpastes that are typically more expensive than those that use sodium fluoride. Stannous fluoride has both bactericidal and bacteriostatic properties, which fight plaque and treat/prevent gingivitis. The stannous fluoride also deposits a protective mineral barrier over exposed dentinal tubules to help prevent sensitivity pain from triggers such as hot or cold liquids and foods. Stannous fluoride is used under the trade name "Fluoristan" in the original formulation of the toothpaste Crest, though it was later replaced with sodium monofluorophosphate, or "Fluoristat". It is the active ingredient in Crest Pro Health brand toothpaste. Crest Pro Health issues a warning on the tube that stannous fluoride may cause staining, which can be avoided by proper brushing, and that its particular formulation is resistant to staining. Any stannous fluoride staining that occurs due to improper brushing is not permanent. Stannous fluoride is also used in Oral-B Pro-Expert. Stannous fluoride is also readily available in over-the-counter rinses.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
ULTRATAG RBC

Approved Use

Technetium Tc 99m-labeled red blood cells are used for blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding.
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Dental
In Vitro Use Guide
Unknown
Name Type Language
STANNOUS CHLORIDE ANHYDROUS
II  
Common Name English
TIN CHLORIDE
Systematic Name English
STANNOUS CHLORIDE [MI]
Common Name English
Stannous chloride [WHO-DD]
Common Name English
STANNOUS CHLORIDE, ANHYDROUS
Common Name English
STANNOUS CHLORIDE ANHYDROUS [II]
Common Name English
STANNOUS CHLORIDE [HSDB]
Common Name English
TIN(II) CHLORIDE
Systematic Name English
TIN CHLORIDE (SNCL2)
Common Name English
STANNOUS CHLORIDE,ANHYDROUS [VANDF]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID8021351
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
CHEBI
78067
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
DAILYMED
R30H55TN67
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
CAS
7772-99-8
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
FDA UNII
R30H55TN67
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-868-0
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
CONCEPT Industrial Aid
PUBCHEM
377800
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
HSDB
582
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
SMS_ID
100000077832
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
NCI_THESAURUS
C77505
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
RXCUI
314853
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY RxNorm
CAS
1344-13-4
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
NON-SPECIFIC STOICHIOMETRY
WIKIPEDIA
TIN(II) CHLORIDE
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY
MERCK INDEX
m10180
Created by admin on Fri Dec 15 15:43:08 GMT 2023 , Edited by admin on Fri Dec 15 15:43:08 GMT 2023
PRIMARY Merck Index