TRIAMCINOLONE ACETONIDE SODIUM PHOSPHATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H30FO9P.2Na
Molecular Weight	558.4413
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRIAMCINOLONE ACETONIDE SODIUM PHOSPHATE

Structure Search

SMILES

[Na+].[Na+].[H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)COP([O-])([O-])=O

InChI

InChIKey=XCMJCLDAGKYHPP-AREPQIRLSA-L

InChI=1S/C24H32FO9P.2Na/c1-20(2)33-19-10-16-15-6-5-13-9-14(26)7-8-21(13,3)23(15,25)17(27)11-22(16,4)24(19,34-20)18(28)12-32-35(29,30)31;;/h7-9,15-17,19,27H,5-6,10-12H2,1-4H3,(H2,29,30,31);;/q;2*+1/p-2/t15-,16-,17-,19+,21-,22-,23-,24+;;/m0../s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17088419

Triamcinolone acetonide- 21-dihydrogen phosphate is the long-acting derivative of a synthetic glucocorticoid triamcinolone. Triamcinolone acetonide has eight times more potency than prednisolone. Triamcinolone acetonide- 21-dihydrogen phosphate used for intravenous injection. It is supposed to be hydrolyzed rapidly in the body to form the free corticoid alcohol.

Approval Year

PubMed

Title	Date	PubMed
Comparison of the hypothalamic-pituitary-adrenal axis susceptibility upon single-dose i.m. depot versus long-acting i.v. triamcinolone acetonide therapy: a direct pharmacokinetic correlation.	2006 Nov	17088419

Sample Use Guides

In Vivo Use Guide

Single injection - 0.2 mg/kg

Route of Administration: Intravenous

Name

Type

Language

TRIAMCINOLONE ACETONIDE SODIUM PHOSPHATE

Official Name

English

ARISTOSOL

Common Name

English

CL 61965

Code

English

Triamcinolone acetonide sodium phosphate [WHO-DD]

Common Name

English

CL-61965

Code

English

9-FLUORO-11.BETA.,16.ALPHA.,17,21-TETRAHYDROXYPREGNA-1,4-DIENE-3,20-DIONE CYCLIC 16,17-ACETAL WITH ACETONE 21-(DISODIUM PHOSPHATE)

Systematic Name

English

9.ALPHA.-FLUORO-16.ALPHA.-HYDROXYPREDNISOLONE 16.ALPHA.,17.ALPHA.-ACETONIDE 21-DISODIUM PHOSPHATE

Systematic Name

English

CL-106359

Code

English

CL 106359

Code

English

9.ALPHA.-FLUORO-11.BETA.,21-DIHYDROXY-16.ALPHA.,17.ALPHA.-(ISOPROPYLIDENEDIOXY)-1,4-PREGNADIENE-3,20-DIONE 21-(DISODIUM PHOSPHATE)

Systematic Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11-HYDROXY-16,17-((1-METHYLETHYLIDENE)BIS(OXY))-21-(PHOSPHONOOXY)-, SODIUM SALT (1:2), (11.BETA.,16.ALPHA.)-

Common Name

English

TRIAMCINOLONE ACETONIDE SODIUM PHOSPHATE [USAN]

Common Name

English

CL-1965

Code

English

SODIUM PHOSPHATE TRIAMCINOLONE ACETONIDE

Common Name

English

TRIAMCINOLONE ACETONIDE 21-DISODIUM PHOSPHATE [MI]

Common Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11-HYDROXY-16,17-((1-METHYLETHYLIDENE)BIS(OXY))-21-(PHOSPHONOOXY)-, DISODIUM SALT, (11.BETA.,16.ALPHA.)-

Common Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11.BETA.,16.ALPHA.,17,21-TETRAHYDROXY-, CYCLIC 16,17-ACETAL WITH ACETONE, 21-(DIHYDROGEN PHOSPHATE), DISODIUM SALT

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521