U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H27ClN2
Molecular Weight 354.916
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZICRONAPINE

SMILES

CN1CCN(CC1(C)C)[C@@H]2C[C@H](C3=C2C=C(Cl)C=C3)C4=CC=CC=C4

InChI

InChIKey=BYPMJBXPNZMNQD-PZJWPPBQSA-N
InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1

HIDE SMILES / InChI
Zicronapine (formerly known as Lu 31-130), an oral antipsychotic that was studied for the treatment of schizophrenia. The drug was used in a phase III clinical trial.

Approval Year

PubMed

PubMed

TitleDatePubMed
A review of the pharmacology, efficacy and tolerability of recently approved and upcoming oral antipsychotics: an evidence-based medicine approach.
2013 Nov
Patents

Sample Use Guides

7.5 mg/day
Route of Administration: Oral
Name Type Language
ZICRONAPINE
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
LU-31-130
Code English
Zicronapine [WHO-DD]
Common Name English
LU 31-130
Code English
zicronapine [INN]
Common Name English
ZICRONAPINE [USAN]
Common Name English
4-[(1R,3S)-6-Chloro-3-phenyl-2,3-dihydro-1H-inden-1-yl]-1,2,2-trimethylpiperazine
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C29710
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
Code System Code Type Description
USAN
ZZ-30
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
SMS_ID
100000175013
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
NCI_THESAURUS
C152950
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
INN
9050
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
ChEMBL
CHEMBL3039528
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
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WIKIPEDIA
ZICRONAPINE
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
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DRUG BANK
DB12188
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
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FDA UNII
QZV11V7G6A
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
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EPA CompTox
DTXSID30168849
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
PUBCHEM
11465618
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
PRIMARY
CAS
170381-16-5
Created by admin on Fri Dec 15 15:59:52 GMT 2023 , Edited by admin on Fri Dec 15 15:59:52 GMT 2023
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