ROFLURANE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C3H4BrF3O
Molecular Weight	192.962
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ROFLURANE

Structure Search

SMILES

COC(F)(F)C(F)Br

InChI

InChIKey=YOQYDUAUSFAUER-UHFFFAOYSA-N

InChI=1S/C3H4BrF3O/c1-8-3(6,7)2(4)5/h2H,1H3

HIDE SMILES / InChI

Description
Sources: https://patents.google.com/patent/US3683092A/en | https://books.google.com/books?id=I0scAQAAMAAJ&focus=searchwithinvolume&q=roflurane | https://books.google.com/books?id=Q2E6AAAAMAAJ&focus=searchwithinvolume&q=roflurane

Roflurane (DA-893) is a fluorinated ether and general inhalation anesthetic. In humans, this compound shows less hypotensive effects than methoxyflurane. Roflurane was never marketed.

Approval Year

Patents

Patents

Name

Type

Language

DA-893

Preferred Name

English

ROFLURANE

Official Name

English

ROFLURANE [USAN]

Common Name

English

ETHANE, 2-BROMO-1,1,2-TRIFLUORO-1-METHOXY-

Systematic Name

English

2-Bromo-1,1,2-trifluoro-ethyl methyl ether

Systematic Name

English

roflurane [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

Code System Code Type Description

INN

1306

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

EVMPD

SUB10359MIG

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

PUBCHEM

12676

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

CAS

679-90-3

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

FDA UNII

QP8Q61T44L

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

EPA CompTox

DTXSID00862367

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

SMS_ID

100000084328

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

WIKIPEDIA

Roflurane

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

NCI_THESAURUS

C152239

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

ChEMBL

CHEMBL2105826

Created by admin on Mon Mar 31 19:21:09 GMT 2025 , Edited by admin on Mon Mar 31 19:21:09 GMT 2025

PRIMARY

ACTIVE MOIETY


					QP8Q61T44L

ROFLURANE