U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C65H85N17O12
Molecular Weight 1296.4771
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LUTRELIN

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](CC2=CNC3=CC=CC=C23)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=C5C=CC=C6)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8

InChI

InChIKey=YGGIRYYNWQICCP-LDRBRYNMSA-N
InChI=1S/C65H85N17O12/c1-5-69-61(91)53-17-11-25-82(53)64(94)47(16-10-24-70-65(66)67)75-62(92)54(26-36(2)3)81(4)63(93)51(29-39-32-72-45-15-9-7-13-43(39)45)79-57(87)48(27-37-18-20-41(84)21-19-37)76-60(90)52(34-83)80-58(88)49(28-38-31-71-44-14-8-6-12-42(38)44)77-59(89)50(30-40-33-68-35-73-40)78-56(86)46-22-23-55(85)74-46/h6-9,12-15,18-21,31-33,35-36,46-54,71-72,83-84H,5,10-11,16-17,22-30,34H2,1-4H3,(H,68,73)(H,69,91)(H,74,85)(H,75,92)(H,76,90)(H,77,89)(H,78,86)(H,79,87)(H,80,88)(H4,66,67,70)/t46-,47-,48-,49-,50-,51+,52-,53-,54-/m0/s1

HIDE SMILES / InChI
Lutrelin is an agonist of gonadotropin-releasing hormone receptor exerting antineoplastic properties.

Approval Year

Name Type Language
LUTRELIN
INN  
INN  
Official Name English
5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TYROSYL-D-TRYPTOPHYL-N-METHYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE
Common Name English
lutrelin [INN]
Common Name English
LUTEINIZING HORMONE-RELEASING FACTOR (PIG), 6-D-TRYPTOPHAN-7-(N-METHYL-L-LEUCINE)-9-(N-ETHYL-L-PROLINAMIDE)-10-DEGLYCINAMIDE-
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1910
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
Code System Code Type Description
PUBCHEM
25077592
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
FDA UNII
QH51543Y7U
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110617
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
INN
5474
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
RXCUI
1426636
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY RxNorm
DAILYMED
QH51543Y7U
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
CAS
66866-63-5
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
NCI_THESAURUS
C87738
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY
EVMPD
SUB08623MIG
Created by admin on Fri Dec 15 16:57:18 GMT 2023 , Edited by admin on Fri Dec 15 16:57:18 GMT 2023
PRIMARY