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Details

Stereochemistry ACHIRAL
Molecular Formula C14H23N3S2
Molecular Weight 297.483
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TAZOMELINE

SMILES

CCCCCCSC1=NSN=C1C2=CCCN(C)C2

InChI

InChIKey=XUHMGFKQBWZWPO-UHFFFAOYSA-N
InChI=1S/C14H23N3S2/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3

HIDE SMILES / InChI
Tazomeline (also known as LY 287041), a neuropsychiatric agent, is a muscarinic M1 acetylcholine receptor agonist that was studied in patients with cognitive dysfunction. Tazomeline participated in clinical trials for the treatment of Alzheimer’s disease and dementia. However, all these studied were discontinued for unknown reasons.

Approval Year

PubMed

PubMed

TitleDatePubMed
Name Type Language
TAZOMELINE
INN  
INN  
Official Name English
LY-287041
Code English
3-(4-(HEXYLTHIO)-1,2,5-THIADIAZOL-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE
Systematic Name English
PYRIDINE, 3-(4-(HEXYLTHIO)-1,2,5-THIADIAZOL-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYL-
Systematic Name English
tazomeline [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C47796
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
Code System Code Type Description
PUBCHEM
131460
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
PRIMARY
FDA UNII
QDP6S14W5W
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
PRIMARY
INN
7629
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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ChEMBL
CHEMBL131819
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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SMS_ID
100000082454
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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EVMPD
SUB10852MIG
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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NCI_THESAURUS
C87693
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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EPA CompTox
DTXSID80157288
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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CAS
131987-54-7
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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WIKIPEDIA
Tazomeline
Created by admin on Fri Dec 15 17:17:22 GMT 2023 , Edited by admin on Fri Dec 15 17:17:22 GMT 2023
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