Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H39NO2 |
| Molecular Weight | 313.5185 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCCCC(=O)NCCO
InChI
InChIKey=GCCFMSAXQJECNH-UHFFFAOYSA-N
InChI=1S/C19H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19(22)20-17-18-21/h21H,2-18H2,1H3,(H,20,22)
N-(2-HYDROXYETHYL)HEPTADECANAMIDE (or heptadecanoyl ethanolamide) is a synthetic analog of palmitoyl ethanolamide (PEA). This analog is unlikely to be present in any natural tissue, and so can be used as an internal standard for quantitative analysis. It was shown, that heptadecanoyl ethanolamide potentiates the Ca2+ influx response to arachidonyl ethanolamide several fold in cells expressing human recombinant VR1.
Approval Year
Sample Use Guides
It was studied the effects of a series of N-acyl ethanolamines upon the Ca2+-influx in hVR1-HEK293 cells in the absence and presence of 1 μM anandamide (AEA). With the exception of N-acyl ethanolamine palmitoylethanolamide (PEA), none of the N-acyl ethanolamines produced a Ca2+-response per se in the hVR1-HEK293 cells. The response to AEA was greatly potentiated by the C12:0, Heptadecanoylethanolamide (C17:0), C18:0 and C18:1 compounds, so that in the case of the C12:0 compound (lauroylethanolamine), the response to 1 μM AEA became maximal.
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53832-59-0
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14455158
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DTXSID10560544
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Q750804J30
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admin on Sat Dec 16 09:35:19 GMT 2023 , Edited by admin on Sat Dec 16 09:35:19 GMT 2023
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SUBSTANCE RECORD
