MYRISTALKONIUM SACCHARINATE

Possibly Marketed Outside US

First approved in 1999

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H42N.C7H4NO3S
Molecular Weight	514.763
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MYRISTALKONIUM SACCHARINATE

Structure Search

SMILES

O=C1[N-]S(=O)(=O)C2=C1C=CC=C2.CCCCCCCCCCCCCC[N+](C)(C)CC3=CC=CC=C3

InChI

InChIKey=VGTOUOZCVUBDBV-UHFFFAOYSA-M

InChI=1S/C23H42N.C7H5NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-18-21-24(2,3)22-23-19-16-15-17-20-23;9-7-5-3-1-2-4-6(5)12(10,11)8-7/h15-17,19-20H,4-14,18,21-22H2,1-3H3;1-4H,(H,8,9)/q+1;/p-1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/25443467
Curator's Comment: description was created based on several sources, including: https://drugs.medelement.com/drug/%D0%A4%D0%B0%D1%80%D0%BC%D0%B0%D1%82%D0%B5%D0%BA%D1%81-20%D0%BC%D0%B3-%D0%B8%D0%BD%D1%81%D1%82%D1%80%D1%83%D0%BA%D1%86%D0%B8%D1%8F?instruction_lang=RU | http://xn-----8kceunaflgjrqyoqfbei8dxl.xn--p1ai/%D0%BC%D0%B8%D1%80%D0%B8%D1%81%D1%82%D0%B0%D0%BB%D0%BA%D0%BE%D0%BD%D0%B8%D1%8F_%D1%85%D0%BB%D0%BE%D1%80%D0%B8%D0%B4

Myristalkonium is used as spermicide in vaginal contraceptives. It has antiseptic properties also. Breastfeeding women might use it because it does not pass into maternal milk. Absorbed only on the surface of the walls of the vagina and then return to normal physiological droppings or eliminates simple washing with water. Adverse effects are: burning, itch, contact dermatitis. Any drug, introduced into the vagina, can inactivate the local spermicidal action of Myristalkonium.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Spermatozoa membranes 4 Target ID: Spermatozoa membranes Sources: https://drugs.medelement.com/drug/%D0%A4%D0%B0%D1%80%D0%BC%D0%B0%D1%82%D0%B5%D0%BA%D1%81-20%D0%BC%D0%B3-%D0%B8%D0%BD%D1%81%D1%82%D1%80%D1%83%D0%BA%D1%86%D0%B8%D1%8F?instruction_lang=RU	Modulator 828

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pregnancy 65 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25443467	Preventing		Approved 8429	Pharmatex Approved Use Myristalkonium is used as spermicide.

PubMed

Title	Date	PubMed
Intrinsic denervation of the colon is associated with a decrease of some colonic preneoplastic markers in rats treated with a chemical carcinogen.	2008 Apr	18297187
Enhancement of the luminescence efficiency of europium(III) tris(β-diketonato) complex in organic media by quaternary ammonium salts with anionic ligands.	2011	22156255
Biosorption of tetradecyl benzyl dimethyl ammonium chloride on activated sludge: kinetic, thermodynamic and reaction mechanisms.	2011 Feb	21195609

Patents

Sample Use Guides

In Vivo Use Guide

Capsule/suppository/tablet injected deep into the vagina at the latest 5-10 minutes before but not longer than 3 hours before sexual intercour.

Route of Administration: Vaginal

In Vitro Use Guide

Unknown

Name

Type

Language

MYRISTALKONIUM SACCHARINATE

Official Name

English

MYRISTYL DIMETHYL BENZYL AMMONIUM SACCHARINATE

Common Name

English

ALKYL(C12-18)DIMETHYLBENZYLAMMONIUM SACCHARINATE

Common Name

English

MYRISTALKONIUM SACCHARINATE [INCI]

Common Name

English

QUATERNIUM 3

Common Name

English

BENZENEMETHANAMINIUM, N,N-DIMETHYL-N-TETRADECYL-, SALT WITH 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE (1:1)

Common Name

English

ALKYL DIMETHYL BENZYL AMMONIUM SACCHARINATE

Common Name

English

QUATERNIUM-3

Common Name

English

BENZENEMETHANAMINIUM, N,N-DIMETHYL-N-TETRADECYL-, SACCHARINATE

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

69171