BENZYLTHIOURACIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10N2OS
Molecular Weight	218.275
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BENZYLTHIOURACIL

Structure Search

SMILES

O=C1NC(=S)NC(CC2=CC=CC=C2)=C1

InChI

InChIKey=PNXBXCRWXNESOV-UHFFFAOYSA-N

InChI=1S/C11H10N2OS/c14-10-7-9(12-11(15)13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,12,13,14,15)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18774123 | https://www.ncbi.nlm.nih.gov/pubmed/27126427 | DOI: 10.1007/s40278-018-48731-1 | https://www.ncbi.nlm.nih.gov/pubmed/7504976 | https://www.ncbi.nlm.nih.gov/pubmed/12428490

Benzylthiouracil is a drug with anti-thyroid activity. It was developed for the treatment of multinodular goiter and hyperthyroidism. Benzylthiouracil treatment associated with severe adverse effects. It has been observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. Benzylthiouracil induced ANCA associated glomerulonephritis in patients with Graves' disease. Benzylthiouracil induces toxic hepatitis and lung damage.

Approval Year

Name

Type

Language

BASDENE

Preferred Name

English

BENZYLTHIOURACIL

Systematic Name

English

NSC-39511

Code

English

BENTIURACIL

Common Name

English

6-BENZYL-2-THIOURACIL

Systematic Name

English

Benzylthiouracil [WHO-DD]

Common Name

English

BENZYLTHIOURACIL [MART.]

Common Name

English

4(1H)-PYRIMIDINONE, 2,3-DIHYDRO-6-(PHENYLMETHYL)-2-THIOXO-

Systematic Name

English

NSC-6508

Code

English

Classification Tree Code System Code

WHO-VATC

QH03BA03

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

WHO-ATC

H03BA03

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

Code System Code Type Description

EVMPD

SUB13040MIG

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

PRIMARY

PUBCHEM

685814

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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ChEMBL

CHEMBL1491306

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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FDA UNII

PZ35LUM333

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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WIKIPEDIA

BENZYLTHIOURACIL

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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ECHA (EC/EINECS)

228-717-6

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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SMS_ID

100000077166

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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NSC

6508

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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MESH

C019269

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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NSC

39511

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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RXCUI

19084

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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RxNorm

DRUG CENTRAL

339

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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DRUG BANK

DB13804

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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CAS

6336-50-1

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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EPA CompTox

DTXSID30873587

Created by admin on Mon Mar 31 18:43:40 GMT 2025 , Edited by admin on Mon Mar 31 18:43:40 GMT 2025

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SUBSTANCE RECORD


					PZ35LUM333

BENZYLTHIOURACIL