U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H28O10
Molecular Weight 428.4303
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ROSARIN

SMILES

OC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC\C=C\C3=CC=CC=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O

InChI

InChIKey=IEBFEMIXXHIISM-YZOUKVLTSA-N
InChI=1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1

HIDE SMILES / InChI
Rosarin has been shown to reduce fatigue, improve exercise endurance, and increase mental performance. Rosarin is a part of Golden root (Roseroot, Rhodiola rosea L., Crassulaceae). The plant is distributed globally in arctic regions, including Northern Asia, Alaska and northern parts of Europe, and it has been connected to number of biological activities, such as effects on prolyl endopeptidase inhibition, antiallergic effects, effect to memory and learning, antidepressant and anti-inflammatory effects and effects in cancer therapy. The main compounds responsible for these activities are believed to be phenylpropanoid tyrosol, its glucoside salidroside, phenylpropenoids rosin, rosarin and rosavin, which are reported to be pharmacologically active as antioxidants and neurostimulants.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Phenylpropane glycosides from Juniperus phoenicea.
1996 Feb
Phenylpropanoid glycosides from Rhodiola rosea.
2003 Apr
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
ROSARIN
Common Name English
ROSARIN (GLYCOSIDE)
Common Name English
ROSARIN (CONSTITUENT OF RHODIOLA ROSEA) [DSC]
Systematic Name English
.BETA.-D-GLUCOPYRANOSIDE, (2E)-3-PHENYL-2-PROPEN-1-YL 6-O-.ALPHA.-L-ARABINOFURANOSYL-
Common Name English
ROSARIN, (-)-
Common Name English
Classification Tree Code System Code
DSLD 3463 (Number of products:2)
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
Code System Code Type Description
PUBCHEM
10320370
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
PRIMARY
FDA UNII
PQA54L0KFI
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
PRIMARY
EPA CompTox
DTXSID601045580
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
PRIMARY
CAS
84954-93-8
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
PRIMARY
WIKIPEDIA
Rosarin
Created by admin on Sat Dec 16 11:13:03 UTC 2023 , Edited by admin on Sat Dec 16 11:13:03 UTC 2023
PRIMARY