Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H8ClNO3 |
Molecular Weight | 201.607 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(C=C(Cl)C(N)=C1)C(O)=O
InChI
InChIKey=RVEATKYEARPWRE-UHFFFAOYSA-N
InChI=1S/C8H8ClNO3/c1-13-7-3-6(10)5(9)2-4(7)8(11)12/h2-3H,10H2,1H3,(H,11,12)
Approval Year
PubMed
Title | Date | PubMed |
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Endogenous 5-HT tonically inhibits spontaneous firing activity of dorsal hippocampus CA1 pyramidal neurons through stimulation of 5-HT(1A) receptors in quiet awake rats: in vivo electrophysiological evidence. | 2001 Feb |
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Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4-dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT3 and dopamine D2 receptors dual antagonist. | 2002 Jul |
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Involvement of the 5-HT(1A) receptor in the anti-immobility effects of fluvoxamine in the forced swimming test and mouse strain differences in 5-HT(1A) receptor binding. | 2010 Mar 10 |
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Antidepressant-like effects of neferine in the forced swimming test involve the serotonin1A (5-HT1A) receptor in mice. | 2010 May 25 |
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7206-70-4
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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PQ8L2L84EL
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230-582-3
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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DTXSID50222391
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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81626
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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SUBSTANCE RECORD