U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H8ClNO3
Molecular Weight 201.607
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-AMINO-5-CHLORO-2-METHOXYBENZOIC ACID

SMILES

COC1=C(C=C(Cl)C(N)=C1)C(O)=O

InChI

InChIKey=RVEATKYEARPWRE-UHFFFAOYSA-N
InChI=1S/C8H8ClNO3/c1-13-7-3-6(10)5(9)2-4(7)8(11)12/h2-3H,10H2,1H3,(H,11,12)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Endogenous 5-HT tonically inhibits spontaneous firing activity of dorsal hippocampus CA1 pyramidal neurons through stimulation of 5-HT(1A) receptors in quiet awake rats: in vivo electrophysiological evidence.
2001 Feb
Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4-dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT3 and dopamine D2 receptors dual antagonist.
2002 Jul
Involvement of the 5-HT(1A) receptor in the anti-immobility effects of fluvoxamine in the forced swimming test and mouse strain differences in 5-HT(1A) receptor binding.
2010 Mar 10
Antidepressant-like effects of neferine in the forced swimming test involve the serotonin1A (5-HT1A) receptor in mice.
2010 May 25
Patents
Name Type Language
4-AMINO-5-CHLORO-2-METHOXYBENZOIC ACID
Systematic Name English
4-AMINO-5-CHLORO-3-METHOXYBENZOIC ACID
Systematic Name English
BENZOIC ACID, 4-AMINO-5-CHLORO-2-METHOXY-
Common Name English
2-METHOXY-4-AMINO-5-CHLOROBENZOIC ACID
Systematic Name English
4-AMINO-5-CHLORO-O-ANISIC ACID
Common Name English
O-ANISIC ACID, 4-AMINO-5-CHLORO-
Common Name English
4-AMINO-5-CHLORO-2-(METHYLOXY)BENZOIC ACID
Systematic Name English
5-CHLORO-4-AMINO-2-METHOXYBENZOIC ACID
Systematic Name English
METOCLOPRAMIDE IMPURITY C [EP IMPURITY]
Common Name English
5-CHLORO-4-AMINO-2-ETHOXYBENZOIC ACID
Systematic Name English
Code System Code Type Description
CAS
7206-70-4
Created by admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
PRIMARY
FDA UNII
PQ8L2L84EL
Created by admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
PRIMARY
ECHA (EC/EINECS)
230-582-3
Created by admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID50222391
Created by admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
PRIMARY
PUBCHEM
81626
Created by admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
PRIMARY