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Details

Stereochemistry ACHIRAL
Molecular Formula C3HCl2N3O3
Molecular Weight 197.964
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TROCLOSENE

SMILES

ClN1C(=O)NC(=O)N(Cl)C1=O

InChI

InChIKey=CEJLBZWIKQJOAT-UHFFFAOYSA-N
InChI=1S/C3HCl2N3O3/c4-7-1(9)6-2(10)8(5)3(7)11/h(H,6,9,10)

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including: http://www.preciseformulation.com/nadcc-tablets-general-applications.html | http://akvopedia.org/wiki/Chlorine_(NaDCC) | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b345ae6a-0b36-45c7-b31e-2a15508a2ef5 | https://www.ncbi.nlm.nih.gov/pubmed/20064989

Troclosene is chlorinated hydroxytriazine and it is used as a source of free available chlorine, in the form of hypochlorous acid, for the disinfection of water. It kills bacteria, bacterial spores, cysts, algae, fungi, protozoa and virus and are especially lethal to Entamoeba histolytica. Troclosene kills mastitis-causing organisms. It is now widely available for household water treatment. It does not prevent diarrhea but improved water quality.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Germicidal activities of representatives of five different teat dip classes against three bovine mycoplasma species using a modified excised teat model.
2002 Aug
Flow-injection chemiluminescence determination of chlorinated isocyanuric acids.
2003 Feb
Determination of decimal reduction time (D value) of chemical agents used in hospitals for disinfection purposes.
2003 Oct 17
Soft tissue dissolution capacity of currently used and potential endodontic irrigants.
2004 Nov
Flow-injection potentiometric determination of triiodide by plasticized poly(vinyl chloride) membrane electrodes and its application to the determination of chlorine-containing disinfectants.
2005 Mar 15
Use of sodium dichloroisocyanurate for floor disinfection.
2009 Jul
Effects of pH and oil-in-water emulsions on growth and physicochemical cell surface properties of Listeria monocytogenes: Impact on tolerance to the bactericidal activity of disinfectants.
2009 Mar 31
Collection of indonaphthol blue on a membrane filter for the spectrophotometric determination of ammonia with 1-naphthol and dichloroisocyanurate.
2010
Improvements to water purification and sanitation infrastructure may reduce the diarrheal burden in a marginalized and flood prone population in remote Nicaragua.
2010 Dec 8
Sodium dichloroisocyanurate tablets for routine treatment of household drinking water in periurban Ghana: a randomized controlled trial.
2010 Jan
Root canal irrigants.
2010 Oct
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Viral suspensions were prepared containing 10(4)-10(5) syncitial forming units ml-1 in 0.9% saline or 0.9% saline containing 10% v/v plasma to simulate clean and dirty conditions. A syncitial inhibition assay on C8166 lymphoblastoid line was used to determine viral titre. Results indicate that satisfactory disinfection (3-4 log reduction in 2 min) can be achieved using Troclosene and NaOCl at concentrations of 50 ppm and 2500 ppm available chlorine (AvCl2) for clean and soiled conditions respectively. For treatment of blood spillages, the addition of Troclosene and NaOCl solutions (10,000 ppm) to equal volumes of contaminated blood (giving a final AvCl2 concentration of 5000 ppm of blood) was sufficient to produce total kill within 2 min.
Name Type Language
TROCLOSENE
HSDB   MART.   WHO-DD  
Common Name English
DICHLOROISOCYANURIC ACID
Systematic Name English
DICHLORO-1,3,5-TRIAZINETRIONE
Systematic Name English
DICHLOROCYANURIC ACID
Systematic Name English
TROCLOSENE [HSDB]
Common Name English
Troclosene [WHO-DD]
Common Name English
1,3,5-TRIAZINE-2,4,6(1H,3H,5H)-TRIONE, 1,3-DICHLORO-
Systematic Name English
1,3-DICHLORO-S-TRIAZINE-2,4,6(1H,3H,5H)TRIONE
Systematic Name English
S-TRIAZINE-2,4,6(1H,3H,5H)-TRIONE, 1,3-DICHLORO-
Systematic Name English
DICHLORO-S-TRIAZINE-2,4,6-TRIONE
Systematic Name English
TROCLOSENE [MART.]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 81401
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
Code System Code Type Description
PUBCHEM
16726
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
CAS
2782-57-2
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
HSDB
5897
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
EPA CompTox
DTXSID8024993
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
MESH
C011765
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
RXCUI
1537576
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
Dichloroisocyanuric acid
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
FDA UNII
PHR838Y52L
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY
ECHA (EC/EINECS)
220-487-5
Created by admin on Fri Dec 15 16:50:10 GMT 2023 , Edited by admin on Fri Dec 15 16:50:10 GMT 2023
PRIMARY