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Details

Stereochemistry ACHIRAL
Molecular Formula C8H5N3O3S2
Molecular Weight 255.2761
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TENONITROZOLE

SMILES

c1cc(C(=O)Nc2ncc(N(=O)=O)s2)sc1

InChI

InChIKey=ZLOXYEZYWCTXHU-UHFFFAOYSA-N
InChI=1S/C8H5N3O3S2/c12-7(5-2-1-3-15-5)10-8-9-4-6(16-8)11(13)14/h1-4H,(H,9,10,12)

HIDE SMILES / InChI
Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
ATRICAN

Approved Use

This medicine contains the active ingredient tenonitrozole which belongs to a group of antiprotozoal agents. This medicine is prescribed for the treatment of urogenital trichomoniasis, which is an infection caused by the parasite Trichomonas vaginalis.
PubMed

PubMed

TitleDatePubMed
[UROGENITAL SYNDROMES CAUSED BY "TRICHOMONAS VAGINALIS" AND "CANDIDA ALBICANS". RESULTS OF TREATMENT BY 2-(ALPHA-THENOYLAMINO)-5-NITROTHIAZOLE].
1963 Dec 28
[THE INFLUENCE OF ATRICAN (ALPHA-THENOYL-AMINO-2-NITRO-5-THIAZOLE) ON THE PREGNANCY AND FETAL DEVELOPMENT OF THE RAT, MOUSE AND RABBIT].
1964 May 20
Development of 5-nitrothiazole derivatives: identification of leads against both replicative and latent Mycobacterium tuberculosis.
2012 Dec 15
Patents

Sample Use Guides

Urogenital trichomoniasis treatment: The usual dose is 1 capsule in the morning and 1 capsule (250 mg) in the evening during meals, for 4 days. Both partners should be treated simultaneously.
Route of Administration: Oral
Tenonitrozole inhibited Giardia with IC50 value of 0.19 uM
Name Type Language
TENONITROZOLE
INN   MART.   MI   WHO-DD  
INN  
Official Name English
N-(5-NITRO-2-THIAZOLYL)-2-THIOPHENECARBOXAMIDE
Systematic Name English
TENONITROZOLE [INN]
Common Name English
TENONITROZOLE [WHO-DD]
Common Name English
TENONITROZOLE [MI]
Common Name English
TENONITROZOLE [MART.]
Common Name English
ATRICAN
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C277
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
WHO-ATC P01AX08
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
Code System Code Type Description
CAS
3810-35-3
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
NCI_THESAURUS
C152561
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
DRUG BANK
DB13659
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
INN
5150
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
ECHA (EC/EINECS)
223-282-9
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
MERCK INDEX
M10560
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY Merck Index
FDA UNII
PBQ7WLE1WP
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
WIKIPEDIA
TENONITROZOLE
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
DRUG CENTRAL
2594
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
RXCUI
236186
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY RxNorm
EVMPD
SUB10897MIG
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
ChEMBL
CHEMBL1082354
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
PUBCHEM
19646
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY
EPA CompTox
3810-35-3
Created by admin on Fri Jun 25 22:43:57 UTC 2021 , Edited by admin on Fri Jun 25 22:43:57 UTC 2021
PRIMARY