Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H14N8O5S4.ClH.H2O |
| Molecular Weight | 569.058 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.[H][C@]12SCC(SCSC3=CNN=N3)=C(N1C(=O)[C@H]2NC(=O)C(=N/O)\C4=CSC(N)=N4)C(O)=O
InChI
InChIKey=LBWIJMWZWJRRMO-AWXOXGPMSA-N
InChI=1S/C15H14N8O5S4.ClH.H2O/c16-15-18-5(2-30-15)8(21-28)11(24)19-9-12(25)23-10(14(26)27)6(3-29-13(9)23)31-4-32-7-1-17-22-20-7;;/h1-2,9,13,28H,3-4H2,(H2,16,18)(H,19,24)(H,26,27)(H,17,20,22);1H;1H2/b21-8-;;/t9-,13-;;/m1../s1
DescriptionCurator's Comment: description was created based on several sources, including
http://google.com/patents/EP0467647B1 | https://www.ncbi.nlm.nih.gov/pubmed/11400306 | https://www.ncbi.nlm.nih.gov/pubmed/8585742 | https://www.ncbi.nlm.nih.gov/pubmed/9612604
Curator's Comment: description was created based on several sources, including
http://google.com/patents/EP0467647B1 | https://www.ncbi.nlm.nih.gov/pubmed/11400306 | https://www.ncbi.nlm.nih.gov/pubmed/8585742 | https://www.ncbi.nlm.nih.gov/pubmed/9612604
Cefmatilen (codenamed S-1090) is an orally-active cephalosporin antibiotic, that shows high activity against a variety of Gram-positive and Gram-negative bacteria, including Streptococcus pyogenes and Neisseria gonorrhoeae.
Originator
Approval Year
Sample Use Guides
The bactericidal activities of S-1090 and the other agents at four times the MIC for Escherichia coli ATCC 25922 were determined. An overnight culture in Mueller-Hinton broth was inoculated into fresh broth, and the mixture was incubated, with constant shaking, until the viability reached 2 3 10^6 to 3 3 10^6 CFU/ml. After the addition of antibiotics, the cultures were incubated at 358C and the number of viable cells was determined.
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154776-45-1
Created by
admin on Sat Dec 16 05:27:03 GMT 2023 , Edited by admin on Sat Dec 16 05:27:03 GMT 2023
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PA4O9CKP1M
Created by
admin on Sat Dec 16 05:27:03 GMT 2023 , Edited by admin on Sat Dec 16 05:27:03 GMT 2023
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9690121
Created by
admin on Sat Dec 16 05:27:03 GMT 2023 , Edited by admin on Sat Dec 16 05:27:03 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
