U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C19H25N4O6PS2
Molecular Weight 500.529
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of UREDOFOS

SMILES

CCOP(=O)(NC(=S)NC1=CC=CC=C1NC(=O)NS(=O)(=O)C2=CC=C(C)C=C2)OCC

InChI

InChIKey=NDXFLHPUUKVXLQ-UHFFFAOYSA-N
InChI=1S/C19H25N4O6PS2/c1-4-28-30(25,29-5-2)22-19(31)21-17-9-7-6-8-16(17)20-18(24)23-32(26,27)15-12-10-14(3)11-13-15/h6-13H,4-5H2,1-3H3,(H2,20,23,24)(H2,21,22,25,31)

HIDE SMILES / InChI
Uredofos is a broad-spectrum anthelmintic. Uredofos is highly effective against canine tapeworms, ascarids, and hookworms when given as a single dose of 50 mg/kg and against whipworm when given at dose level of 50 mg/kg/day for 2 days. In mice complete removal of Hymenolepis nana occurred at 25 mg/kg and Syphacia obvelata was completely eliminated at all levels.

Approval Year

PubMed

PubMed

TitleDatePubMed

Sample Use Guides

Dogs: uredofos is highly effective against canine tapeworms, ascarids, and hookworms when given as a single dose of 50 mg/kg and against whipworm when given at dose level of 50 mg/kg/day for 2 days.
Route of Administration: Oral
Name Type Language
UREDOFOS
INN   USAN  
INN   USAN  
Official Name English
RH-32565
Code English
uredofos [INN]
Common Name English
UREDOFOS [MI]
Common Name English
RH-32,565
Code English
RH-565
Code English
UREDOFOS [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
Code System Code Type Description
INN
4139
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
NCI_THESAURUS
C72154
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
MESH
C012545
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
MERCK INDEX
m12155
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
FDA UNII
P8W25X9B3K
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
SMS_ID
100000076663
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
EVMPD
SUB11386MIG
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
CAS
52406-01-6
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
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EPA CompTox
DTXSID0073534
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
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ChEMBL
CHEMBL2105590
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY
PUBCHEM
3033943
Created by admin on Fri Dec 15 16:35:49 GMT 2023 , Edited by admin on Fri Dec 15 16:35:49 GMT 2023
PRIMARY