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Details

Stereochemistry MIXED
Molecular Formula C15H21NO2
Molecular Weight 247.3327
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRODILIDINE

SMILES

CCC(=O)OC1(CCN(C)C1C)C2=CC=CC=C2

InChI

InChIKey=LUKSBMJXPCFBKO-UHFFFAOYSA-N
InChI=1S/C15H21NO2/c1-4-14(17)18-15(10-11-16(3)12(15)2)13-8-6-5-7-9-13/h5-9,12H,4,10-11H2,1-3H3

HIDE SMILES / InChI
Prodilidine is an arylpyrrolidine derivative patented by Mead Johnson & Co.as moderately potent analgesic. By comparison with other drugs, including morphine, Prodilidine has a prompt and unusually sustained antinociceptive action in rodents by all routes. Prodilidine substantially lacks antipyretic, anti-inflammatory, antitussive, constipating, respiratory depressant, and cardiovascular effects. Prodilidine resembles meperidine in excitatory properties and body-temperature lowering action at high dosage. The d-isomer is about twice as potent and toxic as the l-isomer parenterally; by the gastric route, the difference is markedly less.

Approval Year

PubMed

PubMed

TitleDatePubMed
PRODILIDINE HYDROCHLORIDE: A NEW MODERATELY POTENT ANALGESIC.
1964 Jan
Patents

Patents

Name Type Language
PRODILIDINE
INN  
INN  
Official Name English
1,2-DIMETHYL-3-PHENYL-3-PYRROLIDINOL PROPIONATE (ESTER)
Common Name English
CI-427
Code English
prodilidine [INN]
Common Name English
Code System Code Type Description
PUBCHEM
19514
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
EVMPD
SUB10067MIG
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
EPA CompTox
DTXSID30863261
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
CAS
3734-17-6
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
SMS_ID
100000081137
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
NCI_THESAURUS
C174834
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
WIKIPEDIA
PRODILIDINE
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
FDA UNII
P67JPY18WD
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110974
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY
INN
1098
Created by admin on Fri Dec 15 18:44:26 GMT 2023 , Edited by admin on Fri Dec 15 18:44:26 GMT 2023
PRIMARY