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Details

Stereochemistry ACHIRAL
Molecular Formula C23H28ClN3O2.ClH
Molecular Weight 450.401
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OPC-14523 HYDROCHLORIDE

SMILES

Cl.COC1=C2CCC(=O)N(CCCN3CCN(CC3)C4=CC(Cl)=CC=C4)C2=CC=C1

InChI

InChIKey=SFOVXVXPFWJNBL-UHFFFAOYSA-N
InChI=1S/C23H28ClN3O2.ClH/c1-29-22-8-3-7-21-20(22)9-10-23(28)27(21)12-4-11-25-13-15-26(16-14-25)19-6-2-5-18(24)17-19;/h2-3,5-8,17H,4,9-16H2,1H3;1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate).
2002 Apr
Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.
2004 Aug
Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.
2007 Jan
Name Type Language
OPC-14523 HYDROCHLORIDE
Systematic Name English
2(1H)-QUINOLINONE, 1-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-3,4-DIHYDRO-5-METHOXY-, HYDROCHLORIDE (1:1)
Common Name English
Code System Code Type Description
DRUG BANK
DBSALT002834
Created by admin on Sat Dec 16 13:43:58 GMT 2023 , Edited by admin on Sat Dec 16 13:43:58 GMT 2023
PRIMARY
PUBCHEM
19027727
Created by admin on Sat Dec 16 13:43:58 GMT 2023 , Edited by admin on Sat Dec 16 13:43:58 GMT 2023
PRIMARY
CAS
145969-31-9
Created by admin on Sat Dec 16 13:43:58 GMT 2023 , Edited by admin on Sat Dec 16 13:43:58 GMT 2023
PRIMARY
FDA UNII
OV3VP43XU4
Created by admin on Sat Dec 16 13:43:58 GMT 2023 , Edited by admin on Sat Dec 16 13:43:58 GMT 2023
PRIMARY